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SupplementScience

Types of Avocado Soy Unsaponifiables (ASU): Forms & Bioavailability

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Forms Comparison

FormBioavailabilityBest For
ASU 300 (Piascledine)GoodThe original pharmaceutical-grade product with the strongest clinical evidence (1:2 avocado:soy ratio)
ASU Capsules (OTC)Moderate-GoodOver-the-counter supplements — look for products standardized to 300mg with 1:2 ratio

ASU 300 (Piascledine)

Bioavailability: Good. Best for: The original pharmaceutical-grade product with the strongest clinical evidence (1:2 avocado:soy ratio).

ASU Capsules (OTC)

Bioavailability: Moderate-Good. Best for: Over-the-counter supplements — look for products standardized to 300mg with 1:2 ratio.

References

  1. (). Symptomatic efficacy of avocado/soybean unsaponifiables in the treatment of osteoarthritis of the knee and hip: a prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial. Arthritis & Rheumatism. DOI
  2. (). Randomised, controlled trial of avocado-soybean unsaponifiable (Piascledine) effect on structure modification in hip osteoarthritis: the ERADIAS study. Annals of the Rheumatic Diseases. DOI
  3. (). Symptoms modifying effect of avocado/soybean unsaponifiables (ASU) in knee osteoarthritis. Scandinavian Journal of Rheumatology. DOI
  4. (). Symptomatic efficacy of avocado-soybean unsaponifiables (ASU) in osteoarthritis (OA) patients: a meta-analysis of randomized controlled trials. Osteoarthritis and Cartilage. DOI