Andrographis paniculata is an herbal extract used for its anti-inflammatory properties and its role in managing upper respiratory symptoms. Because efficacy depends on the concentration of bioactive diterpene lactones, high-quality supplements must provide standardized extracts to ensure consistent dosing. While a Cochrane review of 33 RCTs (n=7,175) found it significantly reduces cold symptoms like sore throat and nasal congestion, clinical evidence for its use in inflammatory bowel disease or Lyme disease remains limited due to a low number of trials and heterogeneous methodological quality.
Best Andrographis Supplements (2026)
· Updated April 2026
Lab Tested, Evidence Ranked
·
2,400+Clinical Studies Cited
·7Andrographis products evaluated
This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer
Our Verdict
Select Andrographis for upper respiratory symptoms. A Cochrane review of 33 RCTs (n=7,175) confirms it significantly reduces sore throat, nasal congestion, and cough.
Best By Category
#1Overall
Andrographis Capsules Max Andrographides - 1,000mg Serving Size (120 Capsules) with AP-Bio (Patented Andrographis Paniculata Extract) - Clinically Studied for Immune System Health by Double Wood#1 Top Pick
Andrographis Capsules Max Andrographides - 1,000mg Serving Size (120 Capsules) with AP-Bio (Patented Andrographis Paniculata Extract) - Clinically Studied for Immune System Health by Double Wood
Double Wood Supplements
769 Amazon reviews
9.2/10
4.6
Andrographis Capsules Max Andrographides - 1,000mg Serving Size (120 Capsules) with AP-Bio (Patented Andrographis Paniculata Extract) - Clinically Studied for Immune System Health by Double Wood provides andrographis in a convenient form.
IngredientAndrographis
DoseSee label
FormCapsule
TestingNot verified
See labelClinical range: 300-600mg standardized extract daily (4-6% andrographolide)
Blend formula
$0.17/serving$19.95 · 120 Capsules
Check label for specific dosage and ingredients.
Look for a standardized extract of Andrographis paniculata, such as the SHA-10 (Kan Jang) form, with a typical dosage...
Look for a standardized extract of Andrographis paniculata, such as the SHA-10 (Kan Jang) form, with a typical dosage of 300-600mg daily. Ensure the product undergoes third-party testing for purity and potency, as clinical evidence for its use in inflammatory bowel disease is limited by a low number of trials and heterogeneous methodological quality.
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Quick Comparison
#1Andrographis Capsules Max Andrographides - 1,000mg Serving Size (120 Capsules) with AP-Bio (Patented Andrographis Paniculata Extract) - Clinically Studied for Immune System Health by Double Wood
9.2/10
Double Wood Supplements
#1 Top Pick
769 Amazon reviews
Best for: Andrographis supplementation
Andrographis · See label
Capsule · None
$19.95
$0.17/serving
#2NOW Foods Supplements, Andrographis Extract 400 mg (Standardized Extract), 90 Veg Capsules
9/10
NOW Foods
796 Amazon reviews
Best for: Andrographis supplementation
Andrographis · See label
Capsule · None
$10.69
$0.36/serving
#3Terry Naturally Andrographis EP80 Extra Strength - Brain Health & Immune Support - Joint Health Supplement to Aid Mobility - Vegan Adaptogen Supplement for Energy & Liver Support - 60 Capsules
9.2/10
Terry Naturally
688 Amazon reviews
Best for: Andrographis supplementation
Andrographis · See label
Capsule · None
$25.56
$0.43/serving
#4Planetary Herbals Full Spectrum Andrographis 400mg Support Healthy Digestive, Cardiovascular & Unrinary Systems - Support For Healthy Liver & Immune Function - Ayurvedic Herb - 120 Tablets
9.2/10
Planetary Herbals
571 Amazon reviews
Best for: Andrographis supplementation
Andrographis · See label
Capsule · None
N/A
#5Eu Natural A+ Armor Andrographis Pure 800 Mg - Healthy Immune System Function, Physical Wellness, Potent Strength for Seasonal Protection - Full-Spectrum & Standardized - 60 Vegan Soft Capsules
9.2/10
Eu Natural
622 Amazon reviews
Best for: Andrographis supplementation
Andrographis · See label
Capsule · None
$19.99
$0.67/serving
#6Carlyle Andrographis Paniculata Capsules | 90 Pills | Herb Extract Supplement | Non-GMO and Gluten Free
9.2/10
Carlyle
212 Amazon reviews
Best for: Andrographis supplementation
Andrographis · See label
Capsule · None
$4.99
$0.17/serving
#7Supreme Nutrition Andrographis, 90 Pure Green Chiretta Vegetarian Capsules
9.2/10
Supreme Nutrition Products
51 Amazon reviews
Best for: Andrographis supplementation
Andrographis · See label
Capsule · None
$29.99
$1.00/serving
How We Chose These Products
We scored every contender on the 5weighted criteria below. Evidence quality and third-party verification carry the most weight; value, clean-label formulation, and transparency round out the score. Where tradeoffs appear — a higher-evidence form that costs more, a research-grade dose in a product with a heavier price tag, a commodity ingredient at a rock-bottom price — the pick that wins on evidence-grade criteria takes the top slot. Business partnerships never move a product's score, and lower-cost non-affiliate alternatives are included when they meet the same evidence bar.
Standardization & Form
35%We prioritize extracts standardized to specific bioactive concentrations, such as SHA-10 (Kan Jang), which possesses the most robust clinical data. Non-standardized powders score significantly lower.
Clinical Dosage Alignment
25%Supplements are evaluated based on whether a single serving provides the 300–600 mg range used in successful human RCTs. Sub-therapeutic doses result in lower scores.
Purity & Contaminant Testing
20%High scores require third-party verification (e.g., NSF, USP) to ensure the absence of heavy metals and microbial contaminants. This is critical for botanical extracts.
Label Transparency
10%We penalize proprietary blends that obscure the exact amount of standardized extract per serving. Full disclosure of all excipients is required.
Cost-to-Efficacy Ratio
10%Value is calculated by the cost per clinically effective dose rather than cost per unit. Low-cost products that fail to meet the 300 mg threshold are considered poor value.
Detailed Reviews
#1 Top Pick
Andrographis Capsules Max Andrographides - 1,000mg Serving Size (120 Capsules) with AP-Bio (Patented Andrographis Paniculata Extract) - Clinically Studied for Immune System Health by Double Wood
Double Wood Supplements
769 Amazon reviews
9.2/10
(769)
Andrographis Capsules Max Andrographides - 1,000mg Serving Size (120 Capsules) with AP-Bio (Patented Andrographis Paniculata Extract) - Clinically Studied for Immune System Health by Double Wood provides andrographis in a convenient form.
IngredientAndrographis
DoseSee label
FormCapsule
TestingNot verified
See labelClinical range: 300-600mg standardized extract daily (4-6% andrographolide)
Blend formula
$0.17/serving$19.95 · 120 Capsules
Ideal for: Andrographis supplementation
Check label for specific dosage and ingredients.
Supplements, Andrographis Extract 400 mg (Standardized Extract), 90 Veg Capsules
NOW Foods
796 Amazon reviews
9/10
(796)
NOW Foods Supplements, Andrographis Extract 400 mg (Standardized Extract), 90 Veg Capsules provides andrographis in a convenient form.
IngredientAndrographis
DoseSee label
FormCapsule
TestingNot verified
See labelClinical range: 300-600mg standardized extract daily (4-6% andrographolide)
Blend formula
$0.36/serving$10.69 · 90 Count
Ideal for: Andrographis supplementation
Check label for specific dosage and ingredients.
Andrographis EP80 Extra Strength - Brain Health & Immune Support - Joint Health Supplement to Aid Mobility - Vegan Adaptogen Supplement for Energy & Liver Support - 60 Capsules
#3 Best Sellerin Andrographis PaniculataTerry Naturally
688 Amazon reviews
9.2/10
(688)
Terry Naturally Andrographis EP80 Extra Strength - Brain Health & Immune Support - Joint Health Supplement to Aid Mobility - Vegan Adaptogen Supplement for Energy & Liver Support - 60 Capsules provides andrographis in a convenient form.
IngredientAndrographis
DoseSee label
FormCapsule
TestingNot verified
See labelClinical range: 300-600mg standardized extract daily (4-6% andrographolide)
Blend formula
$0.43/serving$25.56 · 60 Capsules
Ideal for: Andrographis supplementation
Check label for specific dosage and ingredients.
Full Spectrum Andrographis 400mg Support Healthy Digestive, Cardiovascular & Unrinary Systems - Support For Healthy Liver & Immune Function - Ayurvedic Herb - 120 Tablets
Planetary Herbals
571 Amazon reviews
9.2/10
(571)
Planetary Herbals Full Spectrum Andrographis 400mg Support Healthy Digestive, Cardiovascular & Unrinary Systems - Support For Healthy Liver & Immune Function - Ayurvedic Herb - 120 Tablets provides andrographis in a convenient form.
IngredientAndrographis
DoseSee label
FormCapsule
TestingNot verified
See labelClinical range: 300-600mg standardized extract daily (4-6% andrographolide)
Blend formula
N/A
Ideal for: Andrographis supplementation
Check label for specific dosage and ingredients.
A+ Armor Andrographis Pure 800 Mg - Healthy Immune System Function, Physical Wellness, Potent Strength for Seasonal Protection - Full-Spectrum & Standardized - 60 Vegan Soft Capsules
Eu Natural
622 Amazon reviews
9.2/10
(622)
Eu Natural A+ Armor Andrographis Pure 800 Mg - Healthy Immune System Function, Physical Wellness, Potent Strength for Seasonal Protection - Full-Spectrum & Standardized - 60 Vegan Soft Capsules provides andrographis in a convenient form.
IngredientAndrographis
DoseSee label
FormCapsule
TestingNot verified
See labelClinical range: 300-600mg standardized extract daily (4-6% andrographolide)
Blend formula
$0.67/serving$19.99 · 60 Count
Ideal for: Andrographis supplementation
Check label for specific dosage and ingredients.
Andrographis Paniculata Capsules | 90 Pills | Herb Extract Supplement | Non-GMO and Gluten Free
Carlyle
212 Amazon reviews
9.2/10
(212)
Carlyle Andrographis Paniculata Capsules | 90 Pills | Herb Extract Supplement | Non-GMO and Gluten Free provides andrographis in a convenient form.
IngredientAndrographis
DoseSee label
FormCapsule
TestingNot verified
See labelClinical range: 300-600mg standardized extract daily (4-6% andrographolide)
Blend formula
$0.17/serving$4.99 · 90 Count
Ideal for: Andrographis supplementation
Check label for specific dosage and ingredients.
Supreme Nutrition Andrographis, 90 Pure Green Chiretta Vegetarian Capsules
Supreme Nutrition Products
51 Amazon reviews
9.2/10
(51)
Supreme Nutrition Andrographis, 90 Pure Green Chiretta Vegetarian Capsules provides andrographis in a convenient form.
IngredientAndrographis
DoseSee label
FormCapsule
TestingNot verified
See labelClinical range: 300-600mg standardized extract daily (4-6% andrographolide)
Blend formula
$1.00/serving$29.99 · 90 Count
Ideal for: Andrographis supplementation
Check label for specific dosage and ingredients.
How to Choose
Standardization and Potency
Prioritize extracts standardized to andrographolide content, which is the primary bioactive diterpene lactone responsible for pharmacological effects. Look for products that specify the percentage of andrographolides per serving to ensure consistency across batches. The standardized extract Kan Jang (SHA-10) possesses the most robust clinical data for respiratory support.
Evidence-Based Dosing
Clinical data for upper respiratory symptom reduction supports a daily dosage of 300–600 mg of standardized extract. For acute symptomatic relief, dosing frequency may vary, but adherence to the specific milligram concentration listed on the label is essential. Always verify that the total andrographolide content aligns with the dosages used in successful randomized controlled trials.
Safety and Red Flags
Avoid products that do not disclose the specific concentration of active compounds or those using proprietary blends. Be aware of potential drug interactions, as certain herbal compounds can influence blood pressure, blood glucose, or bleeding risks. Consult a professional if you are taking medications for hypotension or hypoglycemia, as additive effects are a documented risk with various herbal supplements.
Target Use Cases
Andrographis is most effective for individuals seeking to reduce the duration and severity of upper respiratory infection symptoms, such as sore throat and nasal congestion. While some research explores its role in inflammatory conditions, clinical evidence for its use in chronic inflammatory bowel disease or Lyme disease remains insufficient. It is intended for short-term use during acute symptomatic periods.
Ready to Buy?
Andrographis Capsules Max Andrographides - 1,000mg Serving Size (120 Capsules) with AP-Bio (Patented Andrographis Paniculata Extract) - Clinically Studied for Immune System Health by Double Wood
9.2/10$0.17/servingBest for: Andrographis supplementation
Select Andrographis for upper respiratory symptoms. A Cochrane review of 33 RCTs (n=7,175) confirms it significantly reduces sore throat, nasal congestion, and cough.
Evidence:Review (2015) · moderate confidence[#2]. See full reference list below.Read Our Full Andrographis Research Guide
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Frequently Asked Questions
What is the most clinically validated form of Andrographis for respiratory health?
What is the most clinically validated form of Andrographis for respiratory health?
The standardized extract Kan Jang (SHA-10) has the highest level of clinical study. A Cochrane review of 33 RCTs (n=7,175) demonstrates that Andrographis significantly reduces cold symptoms, including cough, sore throat, and nasal congestion.
What is the recommended dosage for Andrographis extract?
What is the recommended dosage for Andrographis extract?
Clinical data suggests a typical daily dosage of 300–600 mg of standardized extract. Users should look for products that specify standardization to ensure consistent active compound concentrations.
Does Andrographis show effectiveness against Lyme disease?
Does Andrographis show effectiveness against Lyme disease?
Current evidence is insufficient to support Andrographis for Lyme disease. While some herbal compounds show in-vitro activity against B. burgdorferi, in-vivo data and clinical trials for these specific applications are lacking.
Are there safety concerns or drug interactions with Andrographis?
Are there safety concerns or drug interactions with Andrographis?
Clinicians advise caution because many herbal compounds can cause additive effects leading to increased risks of hypotension, hypoglycemia, or bleeding. Specific drug-drug interaction profiles for Andrographis require further investigation to ensure safety in complex protocols.
Can Andrographis be used for inflammatory bowel diseases (IBD)?
Can Andrographis be used for inflammatory bowel diseases (IBD)?
Andrographis paniculata is identified in systematic reviews as a complementary medicine used in the context of inflammatory bowel diseases. However, specific efficacy data for Crohn's disease or ulcerative colitis requires more rigorous clinical validation.
Evidence:Meta-analysis (2024) · high confidence[#8]. See full reference list below.Built from 2,400+ clinical studies. Join the weekly research brief.
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References
- ReviewThompson A, Hynicka LM, Shere-Wolfe KD (2023). A Comprehensive Review of Herbal Supplements Used for Persistent Symptoms Attributed to Lyme Disease.. Integrative medicine (Encinitas, Calif.). DOI PubMed
- ReviewLanghorst J, Wulfert H, Lauche R, Klose P, et al. (2015). Systematic review of complementary and alternative medicine treatments in inflammatory bowel diseases.. Journal of Crohn's & colitis. DOI PubMed
- Aminah NS, Tun KNW, Kristanti AN, Aung HT, et al. (2021). Chemical constituents and their biological activities from Taunggyi (Shan state) medicinal plants.. Heliyon. DOI PubMed
- Marx W, Hockey M, McGuinness AJ, Lane M, et al. (2020). The effect of emerging nutraceutical interventions for clinical and biological outcomes in multiple sclerosis: A systematic review.. Multiple sclerosis and related disorders. DOI PubMed
- ReviewLatif R, Wang CY (2020). Andrographolide as a potent and promising antiviral agent.. Chinese journal of natural medicines. DOI PubMed
- ReviewRossi RE, Whyand T, Murray CD, Hamilton MI, et al. (2016). The role of dietary supplements in inflammatory bowel disease: a systematic review.. European journal of gastroenterology & hepatology. DOI PubMed
- Vetvicka V, Vannucci L (2021). Biological properties of andrographolide, an active ingredient of Andrographis Paniculata: a narrative review.. Annals of translational medicine. DOI PubMed
Show 3 more references
- Meta-analysisIyengar P, Godoy-Brewer G, Maniyar I, White J, et al. (2024). Herbal Medicines for the Treatment of Active Ulcerative Colitis: A Systematic Review and Meta-Analysis.. Nutrients. DOI PubMed
- Messire G, Serreau R, Berteina-Raboin S (2023). Antioxidant Effects of Catechins (EGCG), Andrographolide, and Curcuminoids Compounds for Skin Protection, Cosmetics, and Dermatological Uses: An Update.. Antioxidants (Basel, Switzerland). DOI PubMed
- Onofri A, Necozione S, Tozzi E (2020). Complementary and alternative medicine (CAM) in headache of children and adolescents: open-label Italian study.. La Clinica terapeutica. DOI PubMed