
Chromium Picolinate 1000mcg - High Absorption and Bioavailability (90 Vegan Safe Capsules, Non-GMO, Gluten Free) by Double Wood Supplements
$0.20/serving
Price verified Apr 22, 2026
Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use
Our verdict
1000mcg chromium per 2-capsule serving of Chromium Picolinate per capsule from Double Wood Supplements. Best for people supporting healthy blood sugar metabolism and macronutrient utilization with a high-absorption chromium form.
Why we recommend this
The picolinate form at 1000mcg is backed by the most robust human clinical trials for chromium and glycemic support. At under $9 for a 45-day supply from a transparent third-party-tested brand, it's one of the most cost-efficient chromium options in the category.
Check for interactions
Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.
Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.
What to watch out for
At 1000mcg, this is a high-dose therapeutic product rather than a nutritional insurance supplement. Users who only need a low-dose micronutrient top-up (adequate via diet) may find 1000mcg unnecessary.
Dose & form
- Serving
- 1000mcg chromium per 2-capsule serving
- Form
- Capsule
- Clinical range
- 200–1000mcg/day; most metabolic studies use 200–400mcg, some insulin-resistance trials use up to 1000mcg
- Dose adequacy
- Full
- Supply
- 45 servings · $0.20/serving
- UPC
- 810142230575
Who it's best for
People supporting healthy blood sugar metabolism and macronutrient utilization with a high-absorption chromium form
Who should skip it
Those needing a lower-dose chromium option — at 1000mcg this exceeds typical daily need and is not suited for general micronutrient top-up
Pros
- 1000mcg per serving — top of the clinical research range for metabolic support
- Picolinate form: best-studied and highest-absorption chromium chelate available
- 45-day supply (90 capsules) at an accessible price point
- Third-party tested, vegan, non-GMO, gluten-free
Cons
- 1000mcg exceeds typical dietary reference intake — not appropriate as a general micronutrient supplement
- Newer ASIN with less review history than other Double Wood products
- Chromium evidence for weight loss specifically is weaker than for glycemic support
What customers say
4.5★ across 3,067 Amazon reviews. The most common questions from shoppers: re any potential interactions with medications, re any side effects from long-term use, and cause any digestive issues or side effects. Full answers in the FAQ below.
Frequently Asked Questions
What is the clinical dose for Chromium Picolinate?
What is the clinical dose for Chromium Picolinate?
Clinical trials typically use 200–1000mcg/day; most metabolic studies use 200–400mcg, some insulin-resistance trials use up to 1000mcg. Double Wood Chromium Picolinate 1000mcg delivers 1000mcg chromium per 2-capsule serving, which we classify as Full relative to that range.
How does Double Wood Chromium Picolinate 1000mcg compare to similar Capsule?
How does Double Wood Chromium Picolinate 1000mcg compare to similar Capsule?
See the "Also consider" section below for two alternatives. Choose based on form preference (Capsule vs alternatives), dose adequacy, and third-party testing.
Is Double Wood Chromium Picolinate 1000mcg third-party tested?
Is Double Wood Chromium Picolinate 1000mcg third-party tested?
Yes — Third-Party Tested (microbes & heavy metals), Non-GMO, Vegan, Gluten-Free. Third-party testing verifies ingredient identity and label accuracy.
Does this work with Amazon Subscribe & Save?
Does this work with Amazon Subscribe & Save?
Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.
Are there any potential interactions with medications?
Are there any potential interactions with medications?
Chromium picolinate can enhance the action of insulin and oral antidiabetic drugs (metformin, sulfonylureas), potentially increasing hypoglycemia risk. It may also interact with NSAIDs (which may increase chromium absorption) and antacids (which may reduce it). Always consult your doctor if you're managing blood sugar with medications.
Are there any side effects from long-term use?
Are there any side effects from long-term use?
Clinical trials using 200–1000mcg daily up to 6 months show good tolerability. At very high doses or with pre-existing kidney/liver conditions, chromium accumulation is theoretically possible. The FDA advises caution above 200mcg for individuals with specific health conditions. Most healthy adults tolerate 1000mcg with no adverse effects.
Does it cause any digestive issues or side effects?
Does it cause any digestive issues or side effects?
Mild GI discomfort (nausea, stomach irritation) is occasionally reported, especially when taken on an empty stomach. Taking with food largely eliminates this. Headaches have been noted in some individuals at higher doses. The picolinate form is generally better tolerated than earlier chromium chloride formulations.
Can it be taken with other supplements or vitamins?
Can it be taken with other supplements or vitamins?
Combines well with berberine, cinnamon, and magnesium for comprehensive metabolic support. Avoid co-administering with calcium carbonate or antacids — they can reduce chromium absorption by up to 50%. Take 2 hours apart from thyroid medications as chromium may affect thyroid hormone metabolism.
Are there any specific instructions for taking it safely?
Are there any specific instructions for taking it safely?
Take 2 capsules daily with a meal. Starting with 1 capsule (500mcg) for the first week allows tolerance assessment. Do not exceed 1000mcg/day from supplements. Individuals with kidney or liver conditions should consult a physician before use at this dose level.
How long until benefits are typically experienced?
How long until benefits are typically experienced?
Chromium picolinate's metabolic effects on insulin sensitivity and glucose metabolism typically require 4–12 weeks of consistent daily use. Studies measuring fasting glucose and HbA1c improvements generally report changes at the 3-month mark. Subjective effects (reduced carb cravings) may be felt earlier by some users.

