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Four Sigmatic Calm Organic Instant Coffee | Medium Roast Arabica with Reishi & Chaga Mushrooms for Stress Relief & Mood Support | USDA Organic | Half Caffeine | 10 Packets — view 1 of 5
Four Sigmatic

Four Sigmatic Calm Organic Instant Coffee | Medium Roast Arabica with Reishi & Chaga Mushrooms for Stress Relief & Mood Support | USDA Organic | Half Caffeine | 10 Packets

4.4· 1,804 Amazon reviews
$12.99$12.34with Subscribe & Save

$1.30/serving

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Price verified Apr 22, 2026

Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use

Our verdict

See label of Anxiety per capsule from Four Sigmatic. Best for anxiety supplementation.

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Why we recommend this

Four Sigmatic Calm Organic Instant Coffee | Medium Roast Arabica with Reishi & Chaga Mushrooms for Stress Relief & Mood Support | USDA Organic | Half Caffeine | 10 Packets provides anxiety in a convenient form.

Check for interactions

Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.

Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.

What to watch out for

Check label for specific dosage and ingredients.

Dose & form

Serving
See label
Form
Capsule
Clinical range
the recommended range
Dose adequacy
Partial
Supply
10 servings · $1.30/serving
UPC
816897020621

Who it's best for

Anxiety supplementation

What customers say

4.4★ across 1,804 Amazon reviews. The most common questions from shoppers: re any potential interactions with medications, re any side effects from long-term use, and cause any digestive issues or side effects. Full answers in the FAQ below.

Frequently Asked Questions

What is the clinical dose for Anxiety?

Clinical trials typically use the recommended range. Four Sigmatic Calm Organic Instant Coffee | Medium Roast Arabica with Reishi & Chaga Mushrooms for Stress Relief & Mood Support | USDA Organic | Half Caffeine | 10 Packets delivers See label, which we classify as Partial relative to that range.

How does Four Sigmatic Calm Organic Instant Coffee | Medium Roast Arabica with Reishi & Chaga Mushrooms for Stress Relief & Mood Support | USDA Organic | Half Caffeine | 10 Packets compare to similar Capsule?

See the "Also consider" section below for two alternatives. Choose based on form preference (Capsule vs alternatives), dose adequacy, and third-party testing.

Is Four Sigmatic Calm Organic Instant Coffee | Medium Roast Arabica with Reishi & Chaga Mushrooms for Stress Relief & Mood Support | USDA Organic | Half Caffeine | 10 Packets third-party tested?

Third-party testing is not disclosed on the label. Contact Four Sigmatic for a Certificate of Analysis.

Does this work with Amazon Subscribe & Save?

Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.

Are there any potential interactions with medications?

Four Sigmatic Calm Organic Instant Coffee | Medium Roast Arabica with Reishi & Chaga Mushrooms for Stress Relief & Mood Support | USDA Organic | Half Caffeine | 10 Packets contains Anxiety. As with any anxiety supplement, consult your healthcare provider if you take prescription medications, especially blood thinners, blood pressure medications, or immunosuppressants. Four Sigmatic recommends consulting a doctor before use if you are on medication.

Are there any side effects from long-term use?

At See label, Four Sigmatic Calm Organic Instant Coffee | Medium Roast Arabica with Reishi & Chaga Mushrooms for Stress Relief & Mood Support | USDA Organic | Half Caffeine | 10 Packets provides a moderate dose within the studied range of the recommended range. Long-term use at recommended doses is generally well-tolerated based on available research. Discontinue and consult a healthcare provider if you experience adverse effects.

Does it cause any digestive issues or side effects?

Anxiety capsules are generally well-tolerated. Four Sigmatic Calm Organic Instant Coffee | Medium Roast Arabica with Reishi & Chaga Mushrooms for Stress Relief & Mood Support | USDA Organic | Half Caffeine | 10 Packets is formulated as a capsule which is designed to be gentle on the stomach. Start with a lower dose if you have a sensitive stomach.

Is this product safe for pregnant or nursing women?

Four Sigmatic does not specifically market Four Sigmatic Calm Organic Instant Coffee | Medium Roast Arabica with Reishi & Chaga Mushrooms for Stress Relief & Mood Support | USDA Organic | Half Caffeine | 10 Packets for pregnant or nursing women. If you are pregnant, nursing, or planning to become pregnant, consult your healthcare provider before taking any anxiety supplement. Clinical safety data during pregnancy is limited for most anxiety products.

Is it safe to take with other supplements?

Four Sigmatic Calm Organic Instant Coffee | Medium Roast Arabica with Reishi & Chaga Mushrooms for Stress Relief & Mood Support | USDA Organic | Half Caffeine | 10 Packets can generally be combined with other supplements, but be mindful of total anxiety intake from all sources to stay within recommended daily limits (the recommended range). Check with your healthcare provider if you're stacking multiple supplements.

What is the recommended dosage?

The recommended dose is See label. Clinical studies on anxiety typically use the recommended range. Four Sigmatic Calm Organic Instant Coffee | Medium Roast Arabica with Reishi & Chaga Mushrooms for Stress Relief & Mood Support | USDA Organic | Half Caffeine | 10 Packets provides a partial dose — consider your total daily intake. Follow the label directions or your healthcare provider's recommendation.

Also consider

Part of this guide

Best Anxiety Supplements

As an Amazon Associate, we earn from qualifying purchases. Some links below are affiliate links — this doesn't affect our editorial independence or product ratings. How we evaluate products

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer