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Life Extension Melatonin 1mg — view 1 of 5
Life Extension

Life Extension Melatonin 1 mg - For Restful Night, Hormone Balance, and Immune Health - Immediate Release - Gluten-Free, Non-GMO - 60 Capsules

4.6· 671 Amazon reviews
$4.39

$0.07/serving

Buy Now on Amazon

Price verified Apr 22, 2026

Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use

Our verdict

1mg per capsule of Melatonin per capsule from Life Extension. Best for overall best at an evidence-based dose.

Third-Party TestedGluten-freeNon-GMOCapsuleSubscribe & Save

Why we recommend this

Provides an optimal 1mg dose — research shows 0.5-1mg is sufficient for most adults and closely mimics the body's natural melatonin production. Life Extension is a research-focused brand with 40+ years of supplement expertise. Clean formula with no fillers or additives.

Check for interactions

Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.

Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.

What to watch out for

Standard capsule (not fast-dissolve). Only 60 capsules per bottle. Some users may prefer a slightly higher dose.

Dose & form

Serving
1mg per capsule
Form
Capsule
Clinical range
0.5-5mg taken 30-60 minutes before bed
Dose adequacy
Therapeutic
Supply
60 servings · $0.07/serving
UPC
737870329060

Who it's best for

Overall best at an evidence-based dose

Who should skip it

Those needing fast onset or doses above 1mg

Pros

  • Evidence-based 1mg dose
  • Research-focused brand (40+ years)
  • Clean formula
  • Excellent value ($0.05/serving)

Cons

  • Not fast-dissolve format
  • Only 60 capsules per bottle
  • Some may need higher dose

What customers say

4.6★ across 671 Amazon reviews. The most common questions from shoppers: life extension melatonin 1mg safe to take with blood pressure medication, i take life extension melatonin 1mg while pregnant or breastfeeding, and melatonin safe for children. Full answers in the FAQ below.

Frequently Asked Questions

What is the clinical dose for Melatonin?

Clinical trials typically use 0.5-5mg taken 30-60 minutes before bed. Life Extension Melatonin 1mg delivers 1mg per capsule, which we classify as Therapeutic relative to that range.

How does Life Extension Melatonin 1mg compare to similar Capsule?

See the "Also consider" section below for two alternatives. Choose based on form preference (Capsule vs alternatives), dose adequacy, and third-party testing.

Is Life Extension Melatonin 1mg third-party tested?

Yes — Third-Party Tested. Third-party testing verifies ingredient identity and label accuracy.

Does this work with Amazon Subscribe & Save?

Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.

Is Life Extension Melatonin 1mg safe to take with blood pressure medication?

You should consult your doctor before combining melatonin with blood pressure medications, as melatonin may affect blood pressure levels. Some studies suggest melatonin can lower blood pressure, which could amplify the effects of antihypertensive drugs. Your healthcare provider can advise on timing and potential interactions.

Can I take Life Extension Melatonin 1mg while pregnant or breastfeeding?

Melatonin supplements are not recommended during pregnancy or breastfeeding due to insufficient safety data. Melatonin plays a role in reproductive hormones, and supplemental doses have not been adequately studied in pregnant or nursing women. Consult your OB-GYN before use.

Is this melatonin safe for children?

This product is formulated for adults. Melatonin use in children should only be done under pediatric guidance, as appropriate doses for children are typically much lower. The American Academy of Pediatrics recommends consulting a pediatrician before giving melatonin to children.

Are there side effects from Life Extension Melatonin 1mg?

At the 1mg dose, side effects are uncommon but may include mild drowsiness, headache, or vivid dreams. The low 1mg dose is less likely to cause next-day grogginess compared to higher-dose melatonin products. If side effects persist, discontinue use and consult your healthcare provider.

Is it safe to take this melatonin long-term?

Short-term use up to 3 months is well-studied and considered safe. Long-term nightly use has less clinical evidence, but no serious safety concerns have emerged in studies lasting up to 2 years. Some experts recommend periodic breaks of 1 week every 2-3 months as a precaution.

When should I take Life Extension Melatonin 1mg?

Take one capsule 30-60 minutes before your target bedtime. Since this is a standard capsule (not fast-dissolve), allowing the full 60 minutes gives your body time to absorb and respond. Avoid bright screens after taking melatonin, as blue light can suppress its effects.

Also consider

Part of this guide

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As an Amazon Associate, we earn from qualifying purchases. Some links below are affiliate links — this doesn't affect our editorial independence or product ratings. How we evaluate products

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer