Life Extension PalmettoGuard® Saw Palmetto, Nettle Root and Beta-Sitosterol, Supports Healthy Prostate Function & Hormone Metabolism, 160 mg of Saw Palmetto for Men, Gluten-Free, Non-GMO, 60 softgels

Clinical trials typically use 60-130mg daily for prostate; 800mg-2g daily for cholesterol. Life Extension Super Saw Palmetto/Nettle Root with Beta-Sitosterol delivers Beta-sitosterol + 320mg saw palmetto + nettle root per serving, which we classify as Full relative to that range.

See the "Also consider" section below for two alternatives. Choose based on form preference (Softgel vs alternatives), dose adequacy, and third-party testing.

Yes — Third-Party Tested. Third-party testing verifies ingredient identity and label accuracy.

Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.

Life Extension PalmettoGuard has a strong safety profile when taken as directed. All three ingredients (saw palmetto, nettle root, beta-sitosterol) have individual clinical evidence supporting daily use for prostate health. Life Extension products undergo rigorous third-party testing for purity.

PalmettoGuard is not known to significantly interact with blood pressure medications. The ingredients primarily act on prostate tissue and cholesterol metabolism rather than cardiovascular function. However, always inform your doctor about all supplements you take.

The saw palmetto component may slightly lower PSA levels. Inform your urologist that you take PalmettoGuard before PSA testing so results can be interpreted in proper context. Do not stop taking the supplement without discussing with your doctor first.

PalmettoGuard is generally well-tolerated. Uncommon side effects may include mild digestive discomfort that typically resolves when taken with food. The combination of ingredients at standard doses has a favorable safety profile based on clinical evidence.

Yes, all three ingredients have been studied in trials lasting 6-12 months with maintained safety profiles. Many men take prostate support supplements like PalmettoGuard indefinitely as part of their health routine. Periodic checkups remain important.

Take 2 softgels daily with a meal. This provides saw palmetto at the full 320mg clinical dose along with therapeutic amounts of nettle root and beta-sitosterol. The 60-softgel bottle provides a 30-day supply at this recommended dose.