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Sports Research Total Omega-3 Fish Oil 2200mg (Multi-Source) — view 1 of 5
Sports Research

Sports Research® Total Omega-3 Fish Oil 2200mg - Made from Antarctic Krill w/Astaxanthin, Wild Sockeye Salmon & Alaska Pollock - 960mg of EPA & DHA - 120 Softgels

4.7· 1,404 Amazon reviews
$43.95$39.55with Subscribe & Save

$0.37/serving

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Price verified Apr 22, 2026

Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use

Our verdict

2200mg total omega-3s per serving; 960mg EPA+DHA of Multi-Source Omega-3 Complex (Alaska Pollock + Antarctic Krill + Wild Sockeye Salmon + Calanus Oil) per softgel from Sports Research. Best for…

Third-Party TestedContains fish (Pollock, Salmon) and shellfish (krill)Gluten-free, soy-freeSoftgelSubscribe & Save

Why we recommend this

This is the most scientifically sophisticated omega-3 in Sports Research's lineup — the wax ester (Calanus) + phospholipid (krill) + triglyceride (fish oil) triple absorption pathway is genuinely unique and represents the frontier of omega-3 bioavailability science. For users who want the most comprehensive daily omega-3 possible and are willing to invest in the premium tier, this is the best choice in the SR lineup.

Check for interactions

Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.

Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.

What to watch out for

The multi-source complexity means more allergen exposures and a higher price point. The 960mg EPA+DHA, while solid, is slightly less than SR's simpler Triple Strength fish oil at 1040mg. Buyers should evaluate whether the multi-source absorption advantage justifies the cost premium over simpler omega-3 formulas.

Dose & form

Serving
2200mg total omega-3s per serving; 960mg EPA+DHA
Form
Softgel
Clinical range
1,000-2,000mg combined EPA+DHA daily
Dose adequacy
Full
Supply
120 servings · $0.37/serving
UPC
023249012825

Who it's best for

Those wanting the most comprehensive multi-source omega-3 in SR's lineup with both wax ester and phospholipid delivery

Who should skip it

Budget-conscious buyers — at $43.95 this is SR's premium omega-3 tier

Pros

  • The only omega-3 supplement combining wax esters (Calanus) and phospholipids (krill) for dual-pathway absorption
  • 2200mg total omega-3s per serving — highest total omega-3 content in SR's lineup
  • Includes built-in astaxanthin antioxidant from Antarctic krill for oil freshness protection
  • 120-count bottle provides 60+ days of supply depending on serving size

Cons

  • At $43.95, this is SR's most expensive omega-3 — premium sourcing carries premium price
  • Contains both fish and shellfish allergens — limits audience versus single-source products
  • 960mg EPA+DHA is lower than SR's Triple Strength (1040mg) despite 2200mg total omega-3s due to other fatty acid sources

What customers say

4.7★ across 1,404 Amazon reviews. The most common questions from shoppers: re any potential interactions with medications, re any side effects from long-term use, and cause any digestive issues or side effects. Full answers in the FAQ below.

Frequently Asked Questions

What is the clinical dose for Multi-Source Omega-3 Complex (Alaska Pollock + Antarctic Krill + Wild Sockeye Salmon + Calanus Oil)?

Clinical trials typically use 1,000-2,000mg combined EPA+DHA daily. Sports Research Total Omega-3 Fish Oil 2200mg (Multi-Source) delivers 2200mg total omega-3s per serving; 960mg EPA+DHA, which we classify as Full relative to that range.

How does Sports Research Total Omega-3 Fish Oil 2200mg (Multi-Source) compare to similar Softgel?

See the "Also consider" section below for two alternatives. Choose based on form preference (Softgel vs alternatives), dose adequacy, and third-party testing.

Is Sports Research Total Omega-3 Fish Oil 2200mg (Multi-Source) third-party tested?

Yes — Yes — third-party tested for heavy metals, PCBs, rancidity; Non-GMO Verified. Third-party testing verifies ingredient identity and label accuracy.

Does this work with Amazon Subscribe & Save?

Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.

Are there any potential interactions with medications?

The combined EPA+DHA content (960mg) may mildly enhance blood-thinning effects of warfarin or aspirin therapy. Krill's phospholipid-bound omega-3s also have antiplatelet properties. Consult your physician if you are on anticoagulant medications or have a scheduled surgery. MCT oil or astaxanthin at these amounts are generally medication-neutral.

Are there any side effects from long-term use?

Long-term multi-source omega-3 supplementation at these doses is well-tolerated based on clinical research on individual omega-3 sources. The inclusion of astaxanthin provides antioxidant protection against lipid peroxidation from the oils. Monitor for any GI sensitivity long-term, particularly if dose is increased.

Does it cause any digestive issues or side effects?

Multi-source oil blends can occasionally cause mild burping if oil oxidation is present, but third-party testing for freshness minimizes rancidity-related GI issues. The astaxanthin provides additional antioxidant stability. Taking with a meal reduces any GI sensitivity for most users.

Can it be taken with other supplements or vitamins?

This formula already contains astaxanthin, so avoid doubling up with separate astaxanthin supplements. It pairs well with vitamin D3, CoQ10, and magnesium. Given the shellfish (krill) content, check for interactions with any shellfish-related protocols or medications.

Are there any specific instructions for taking it safely?

Take with a fat-containing meal for best absorption and to reduce GI sensitivity. Check for fish and shellfish allergy before use. Not suitable for anyone with fish or shellfish allergies. Store in a cool location and refrigerate after opening for maximum freshness of the multi-source oil blend.

How long until benefits are typically experienced?

Measurable omega-3 index improvement occurs within 4–8 weeks of daily supplementation. The Calanus wax ester form has a longer absorption timeline than standard fish oil triglycerides. Full anti-inflammatory and cardiovascular omega-3 benefits develop over 3–6 months of consistent use.

Also consider

Part of this guide

Best Omega-3 & Fish Oil Supplements

As an Amazon Associate, we earn from qualifying purchases. Some links below are affiliate links — this doesn't affect our editorial independence or product ratings. How we evaluate products

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer