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THORNE

Thorne 5-Hydroxytryptophan

4.6· 1,007 Amazon reviews
$38.30$37.05 with Subscribe & Save

$0.43 / count

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Price verified Oct 26, 2026

As an Amazon Associate, we earn from qualifying purchases · Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use

Our verdict

5-HTP with vitamin B6 as P5P: 100 mg 5-HTP + 6.8 mg vitamin B6 per 2 capsules from THORNE. Best for adults reviewing a 5-HTP/B6 formula with their clinician.

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Why we recommend this

The current Thorne 5-Hydroxytryptophan panel lists 100 mg 5-HTP and 6.8 mg vitamin B6 as P5P in two capsules. The 90 capsule bottle provides 45 servings. 100 mg is the two-capsule amount, not the amount in one capsule.

Check for interactions

Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.

Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.

What to watch out for

This is a 5-HTP/B6 combination rather than a single-ingredient 100 mg capsule. Product labeling and ingredient mechanisms do not establish a reliable treatment for mood or sleep problems.

Dose & form

Serving
100 mg 5-HTP + 6.8 mg vitamin B6 per 2 capsules
Form
Capsule
Supply
45 servings · $0.43 / count
UPC
693749503026

Who it's best for

Adults reviewing a 5-HTP/B6 formula with their clinician

Who should skip it

Unsupervised combination with antidepressants

Pros

  • 100 mg 5-HTP per two capsules
  • 6.8 mg P5P vitamin B6
  • 45 servings

Cons

  • This is a 5-HTP/B6 combination rather than a single-ingredient 100 mg capsule. Product labeling and ingredient mechanisms do not establish a reliable treatment for mood or sleep problems.

Ratings and product questions

4.6★ across 1,007 Amazon reviews recorded. Explore the product questions below for label and use information.

Frequently Asked Questions

What dose does Thorne 5-Hydroxytryptophan provide?

The recorded label dose is 100 mg 5-HTP + 6.8 mg vitamin B6 per 2 capsules. A clinical dose comparison cannot be made from the available product information. Follow the current product label and your clinician’s advice.

How does Thorne 5-Hydroxytryptophan compare to similar Capsule?

Compare the recorded ingredient amounts, serving size, product form (Capsule), price, and the scope of any testing evidence. Use the linked comparison or brand pages to review available alternatives.

Is Thorne 5-Hydroxytryptophan third-party tested?

Independent product testing has not been verified in this record. Check the manufacturer or certifier for evidence covering this exact product and, where applicable, its lot.

Does this work with Amazon Subscribe & Save?

Subscribe & Save is listed in the product record. Check the current availability, terms, and price on Amazon before enrolling; the record does not guarantee a price for future deliveries.

Which version of Thorne 5-Hydroxytryptophan is covered here?

The current Thorne 5-Hydroxytryptophan panel lists 100 mg 5-HTP and 6.8 mg vitamin B6 as P5P in two capsules. The 90 capsule bottle provides 45 servings. 100 mg is the two-capsule amount, not the amount in one capsule.

What limits should I consider for this exact formula?

This is a 5-HTP/B6 combination rather than a single-ingredient 100 mg capsule. Product labeling and ingredient mechanisms do not establish a reliable treatment for mood or sleep problems.

What should I check before using this product?

The manufacturer warns about antidepressants, including SSRIs and MAOIs, and says not to use during pregnancy or nursing. Review all serotonergic medicines before use.

How should I interpret the serving instructions?

Use the serving instructions on the exact current package. A bottle count, ingredient study or claimed herb equivalent is not a reason to increase the labeled serving.

Also consider

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As an Amazon Associate, we earn from qualifying purchases. Some links below are affiliate links — this doesn't affect our editorial independence or product ratings. How we evaluate products

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer