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Vital Proteins Collagen Peptides — view 1 of 5
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Vital Proteins Collagen Peptides Powder Advanced with Hyaluronic Acid & Vitamin C, 20oz Collagen Protein, Unflavored, 27 Servings

4.5· 213,092 Amazon reviews
$42.99$40.84with Subscribe & Save

$1.54/serving

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Price verified Apr 22, 2026

Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use

Our verdict

20g collagen per serving (2 scoops) of Hydrolyzed Bovine Collagen (Types I & III) per powder from vital proteins. Best for overall best collagen peptides.

Third-Party TestedPowderSubscribe & SaveClinical Dose

Why we recommend this

The category leader with over 100,000 Amazon reviews and a 4.6-star average. Sourced from grass-fed, pasture-raised bovine hides. Provides a full 20g of hydrolyzed collagen per two-scoop serving with 18g protein. Dissolves cleanly in hot or cold liquids. Includes hyaluronic acid and vitamin C in the original formula to support collagen synthesis.

Check for interactions

Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.

Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.

What to watch out for

Premium price compared to competitors. Two-scoop serving may be inconvenient. Unflavored version has a mild bovine taste some users notice in cold water.

Dose & form

Serving
20g collagen per serving (2 scoops)
Form
Powder
Clinical range
10-15 g daily
Dose adequacy
Full
Supply
28 servings · $1.54/serving
UPC
850008654497

Who it's best for

Overall best collagen peptides

Who should skip it

Budget shoppers or those with bovine allergies.

Pros

  • 20g collagen per serving (clinical dose)
  • Grass-fed, pasture-raised bovine
  • Over 100,000 reviews, 4.6 stars
  • Dissolves in hot or cold liquids

Cons

  • Premium price ($1.50/serving)
  • Two-scoop serving size
  • Mild taste in cold water

What customers say

4.5★ across 213,092 Amazon reviews. The most common questions from shoppers: re any drug interactions with vital proteins collagen peptides, vital proteins collagen peptides cause digestive side effects, and safe to take vital proteins collagen peptides during pregnancy. Full answers in the FAQ below.

Frequently Asked Questions

What is the clinical dose for Hydrolyzed Bovine Collagen (Types I & III)?

Clinical trials typically use 10-15 g daily. Vital Proteins Collagen Peptides delivers 20g collagen per serving (2 scoops), which we classify as Full relative to that range.

How does Vital Proteins Collagen Peptides compare to similar Powder?

See the "Also consider" section below for two alternatives. Choose based on form preference (Powder vs alternatives), dose adequacy, and third-party testing.

Is Vital Proteins Collagen Peptides third-party tested?

Yes — Third-Party Tested. Third-party testing verifies ingredient identity and label accuracy.

Does this work with Amazon Subscribe & Save?

Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.

Are there any drug interactions with Vital Proteins Collagen Peptides?

Collagen peptides are generally well-tolerated and have no widely documented drug interactions. However, if you take blood thinners or antibiotics, consult your doctor before starting any new supplement. The hydrolyzed bovine collagen in this product is a food-grade protein, not a pharmacological compound.

Can Vital Proteins Collagen Peptides cause digestive side effects?

Most users tolerate this product well, as reflected by its 4.4-star rating across over 212,000 Amazon reviews. Some people may experience mild bloating or a feeling of fullness when first starting collagen, especially at the full 20g dose. Starting with one scoop and gradually increasing can help minimize any digestive adjustment.

Is it safe to take Vital Proteins Collagen Peptides during pregnancy?

While collagen is a naturally occurring protein, there is limited clinical research on collagen supplementation during pregnancy or breastfeeding. Consult your OB-GYN or midwife before adding this or any supplement to your prenatal routine. The product does not carry a specific pregnancy warning on the label.

Can I take Vital Proteins Collagen Peptides with other supplements?

Yes, collagen peptides are commonly stacked with vitamin C (which supports collagen synthesis), biotin, and omega-3 fatty acids without issues. The product already includes hyaluronic acid and vitamin C in the original formula. Avoid taking it simultaneously with high-calcium supplements, as both compete for absorption.

Is Vital Proteins Collagen Peptides safe for long-term daily use?

Yes, hydrolyzed collagen peptides are considered safe for long-term daily supplementation. Clinical trials lasting up to 12 months show no adverse effects at doses of 2.5-15g daily. Vital Proteins has been available since May 2014, and many customers report using it consistently for years.

How long does it take to see results from Vital Proteins Collagen Peptides?

Most clinical studies show measurable improvements in skin hydration and elasticity after 8-12 weeks of consistent daily use. Hair and nail benefits may take 3-6 months to become noticeable. Consistency is more important than dose — take it daily for best results.

Also consider

Part of this guide

Best Collagen Peptide Supplements

As an Amazon Associate, we earn from qualifying purchases. Some links below are affiliate links — this doesn't affect our editorial independence or product ratings. How we evaluate products

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer