Astragalus — Frequently Asked Questions
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Frequently Asked Questions
Can astragalus prevent colds and flu?
Can astragalus prevent colds and flu?
Astragalus has been traditionally used for immune prevention and there is moderate evidence supporting this use. It enhances innate immunity by stimulating macrophage and NK cell activity, and supports adaptive immunity by promoting T-cell maturation. Taking it consistently during cold and flu season (not during active infection) may help reduce susceptibility. However, avoid astragalus during acute infections — TCM practitioners traditionally contraindicate it during active illness.
What is TA-65 (cycloastragenol)?
What is TA-65 (cycloastragenol)?
TA-65 is a patented, purified form of cycloastragenol — a compound isolated from astragalus root that activates telomerase, the enzyme that maintains telomere length. Shorter telomeres are associated with aging and age-related diseases. A 2011 pilot study showed TA-65 improved immune cell telomere length. However, TA-65 supplements are expensive ($200-600/month), the evidence is limited, and the long-term safety of telomerase activation is not fully understood.
Is astragalus safe during cancer treatment?
Is astragalus safe during cancer treatment?
Several meta-analyses suggest astragalus may improve immune function and reduce side effects when used alongside chemotherapy, particularly in Chinese oncology practice. However, because astragalus stimulates the immune system, it could theoretically interfere with immunosuppressive cancer treatments. Always consult with your oncologist before using astragalus during cancer treatment.
References
- McCulloch M, See C, Shu XJ, et al. (2006). Astragalus-based Chinese herbs and platinum-based chemotherapy for advanced non-small-cell lung cancer: meta-analysis. Journal of Clinical Oncology. DOI PubMed
- Harley CB, Liu W, Blasco M, et al. (2011). A natural product telomerase activator as part of a health maintenance program. Rejuvenation Research. DOI PubMed