General Dosage
250-500mg yeast beta-1,3/1,6-glucan daily
Maximum dose: No established upper limit; clinical trials have used up to 1000mg/day without adverse effects
Beta-Glucans Dosage Guide
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 250-500mg yeast beta-1,3/1,6-glucan daily
Timing: Morning on an empty stomach for optimal absorption via gut-associated lymphoid tissue (GALT)
Dosage by Condition
Daily immune support
250-500mg yeast beta-glucan dailyModerate
Cold season protection
500-900mg daily during fall/winterModerate
Exercise-induced immune suppression
250mg Wellmune dailyModerate
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Daily immune support | 250-500mg yeast beta-glucan daily | Moderate |
| Cold season protection | 500-900mg daily during fall/winter | Moderate |
| Exercise-induced immune suppression | 250mg Wellmune daily | Moderate |
Upper limit: No established upper limit; clinical trials have used up to 1000mg/day without adverse effects
Timing & Absorption
Morning on an empty stomach for optimal absorption via gut-associated lymphoid tissue (GALT)
Can be taken with or without food.
References
- Auinger A, Riede L, Bothe G, Busch R, Gruenwald J (2013). Yeast (1,3)-(1,6)-beta-glucan helps to maintain the body's defence against pathogens: a double-blind, randomized, placebo-controlled, multicentric study in healthy subjects. European Journal of Nutrition. DOI PubMed
- Netea MG, Quintin J, van der Meer JW (2011). Trained immunity: a memory for innate host defense. Cell Host & Microbe. DOI PubMed