General Dosage
2.5-5 mg (2,500-5,000 mcg) daily
Maximum dose: No established upper limit; doses up to 10 mg/day are used clinically without toxicity
Biotin Dosage Guide
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 2.5-5 mg (2,500-5,000 mcg) daily
Timing: Can be taken at any time of day
Dosage by Condition
Brittle nails
2.5 mg daily for 6+ monthsModerate
Hair thinning (with deficiency)
5 mg dailyModerate
General maintenance
30-100 mcg daily (adequate intake)Strong
Biotin deficiency
5-10 mg daily under medical supervisionStrong
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Brittle nails | 2.5 mg daily for 6+ months | Moderate |
| Hair thinning (with deficiency) | 5 mg daily | Moderate |
| General maintenance | 30-100 mcg daily (adequate intake) | Strong |
| Biotin deficiency | 5-10 mg daily under medical supervision | Strong |
Upper limit: No established upper limit; doses up to 10 mg/day are used clinically without toxicity
Timing & Absorption
Can be taken at any time of day
Can be taken with or without food.
References
- Patel DP, Swink SM, Castelo-Soccio L. (2017). A review of the use of biotin for hair loss. Skin Appendage Disorders. DOI PubMed
- Colombo VE, Gerber F, Bronhofer M, Floersheim GL. (1990). Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy. Journal of the American Academy of Dermatology. DOI PubMed
- Lipner SR. (2018). Rethinking biotin therapy for hair, nail, and skin disorders. Journal of the American Academy of Dermatology. DOI PubMed
- U.S. Food and Drug Administration. (2017). The FDA warns that biotin may interfere with lab tests: FDA Safety Communication. FDA Safety Communication.