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Types of Citrulline Malate: Forms & Bioavailability

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Forms Comparison

FormBioavailabilityBest For
Citrulline Malate 2:1HighPre-workout — most researched ratio; provides ~4 g citrulline + ~2 g malate per 6 g dose
Pure L-CitrullineHighHigher citrulline per gram — 3-6 g pure citrulline equivalent to 6-8 g citrulline malate
Citrulline Malate 1:1HighEqual ratio — less common, fewer studies; higher malate proportion

Citrulline Malate 2:1

Bioavailability: High. Best for: Pre-workout — most researched ratio; provides ~4 g citrulline + ~2 g malate per 6 g dose.

Pure L-Citrulline

Bioavailability: High. Best for: Higher citrulline per gram — 3-6 g pure citrulline equivalent to 6-8 g citrulline malate.

Citrulline Malate 1:1

Bioavailability: High. Best for: Equal ratio — less common, fewer studies; higher malate proportion.

References

  1. (). Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. Journal of Strength and Conditioning Research. DOI
  2. (). Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine. British Journal of Clinical Pharmacology. DOI
  3. (). Oral L-citrulline supplementation enhances cycling time trial performance. Journal of the International Society of Sports Nutrition. DOI