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DHEA — Frequently Asked Questions

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

Frequently Asked Questions

Should I test my DHEA-S levels before supplementing?

Yes. DHEA-S blood testing is strongly recommended before starting supplementation. Normal ranges vary by age and sex, and supplementing without knowing your baseline can lead to supraphysiological levels and side effects. A healthcare provider can help interpret results and determine an appropriate dose. Retest DHEA-S levels 4-6 weeks after starting supplementation.

Is DHEA safe for women?

DHEA can be safe for women at appropriate doses (typically 5-25mg daily), which is lower than the standard male dose. Women are more susceptible to androgenic side effects like acne, hair growth, and deepening voice at higher doses because DHEA converts to testosterone. Women should start at 5-10mg and increase only under medical supervision with hormone level monitoring.

At what age should I consider DHEA supplementation?

DHEA levels begin declining in the late 20s and drop significantly after age 40. Most clinicians recommend considering DHEA supplementation only after age 40, and only if DHEA-S blood levels are confirmed to be below the reference range for your age. Younger adults generally do not benefit from supplementation unless they have adrenal insufficiency or a documented deficiency.

Full DHEA Guide

References

  1. (). Dehydroepiandrosterone replacement in women with adrenal insufficiency. New England Journal of Medicine. DOI
  2. (). Efficacy of intravaginal dehydroepiandrosterone (DHEA) on moderate to severe dyspareunia and vaginal dryness. Menopause. DOI
  3. (). Effects of dehydroepiandrosterone replacement therapy on bone mineral density in older adults: a randomized, controlled trial. Journal of Clinical Endocrinology & Metabolism. DOI