General Dosage
50-200mcg twice daily, with cycling recommended (5 days on, 2 days off)
Maximum dose: 400mcg/day (note: this is micrograms, not milligrams)
Huperzine A Dosage Guide
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 50-200mcg twice daily, with cycling recommended (5 days on, 2 days off)
Timing: Twice daily (morning and early afternoon); cycle 5 days on, 2 off due to long half-life
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Memory enhancement | 50-200mcg twice daily | Moderate |
| Neuroprotection | 200mcg twice daily | Emerging |
| Study/learning aid | 50-100mcg twice daily | Emerging |
Upper limit: 400mcg/day (note: this is micrograms, not milligrams)
Timing & Absorption
Twice daily (morning and early afternoon); cycle 5 days on, 2 off due to long half-life
Can be taken with or without food.
References
- Xu SS, Gao ZX, Weng Z, et al. (1999). Efficacy of tablet huperzine-A on memory, cognition, and behavior in Alzheimer's disease. Acta Pharmacologica Sinica. PubMed
- Yang G, Wang Y, Tian J, Liu JP (2013). Huperzine A for Alzheimer's disease: a systematic review and meta-analysis of randomized clinical trials. PLoS ONE. DOI PubMed
- Sun QQ, Xu SS, Pan JL, et al. (1999). Huperzine-A capsules enhance memory and learning performance in 34 pairs of matched adolescent students. Acta Pharmacologica Sinica. PubMed