Skip to main content
SupplementScience

Olive Leaf Extract Side Effects & Safety

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

Safety Profile

Overall safety rating: Generally Safe

Potential Side Effects

  • Generally well-tolerated
  • Mild GI symptoms (nausea, acid reflux) in some individuals
  • Herxheimer-like die-off reactions reported anecdotally when starting supplementation (headache, fatigue)
  • May lower blood pressure — beneficial for most but monitor if already on antihypertensives

Drug & Supplement Interactions

  • Antihypertensive medications — olive leaf extract may lower blood pressure; monitor for additive effects
  • Diabetes medications — may lower blood glucose; monitor levels
  • Blood thinners — theoretical antiplatelet effects; consult physician

Maximum Dose

Do not exceed: No established upper limit; doses up to 1500mg/day used without adverse effects in studies

References

  1. (). Effects of the olive-derived polyphenol oleuropein on human health. International Journal of Molecular Sciences. DOI
  2. (). The olive leaf extract exhibits antiviral activity against viral haemorrhagic septicaemia rhabdovirus (VHSV). Antiviral Research. DOI