Safety Profile
Overall safety rating: Generally Safe
Pelargonium (Umcka) Side Effects & Safety
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Potential Side Effects
- Generally well-tolerated in clinical trials
- Mild GI upset (stomach discomfort, nausea, heartburn) in some users
- Rare allergic reactions including skin rash
- Very rare hepatotoxicity cases reported — likely idiosyncratic; liver safety overall is reassuring in clinical trial data
- Rare gum bleeding reported
Drug & Supplement Interactions
- Anticoagulants — pelargonium may increase bleeding risk; use with caution if on warfarin or other blood thinners
- Immunosuppressants — pelargonium stimulates immune function; potential interaction with immunosuppressive therapy
- No other significant drug interactions identified in clinical studies
Maximum Dose
Do not exceed: Follow product labeling; clinical trials used the above doses for up to 14 days
References
- Timmer A, Gunther J, Motschall E, Rucker G, Antes G, Kern WV (2013). Pelargonium sidoides extract for treating acute respiratory tract infections. Cochrane Database of Systematic Reviews. DOI PubMed
- Matthys H, Eisebitt R, Seith B, Heger M (2003). Efficacy and safety of an extract of Pelargonium sidoides (EPs 7630) in adults with acute bronchitis. Phytomedicine. DOI PubMed