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Probiotics (Lactobacillus) — Frequently Asked Questions

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

Frequently Asked Questions

What is the best Lactobacillus strain for IBS?

L. plantarum 299v has the strongest evidence for IBS, with a 2012 RCT (n=214) showing significant reduction in abdominal pain and bloating. L. rhamnosus GG also has supporting evidence. Choose a product that specifies the exact strain designation, not just the species name.

Do Lactobacillus probiotics need to be refrigerated?

Not necessarily. Modern freeze-drying technology allows many Lactobacillus supplements to remain stable at room temperature. However, refrigerated products generally guarantee higher viable counts at expiration. Check the label for storage instructions and look for "viable at expiration" guarantees rather than "at time of manufacture."

Can I take Lactobacillus probiotics with antibiotics?

Yes, and this is actually one of the best-supported uses. Take the probiotic at least 2 hours apart from the antibiotic dose to avoid killing the probiotic organisms. Continue for at least 1-2 weeks after finishing the antibiotic course. L. rhamnosus GG has the strongest evidence for preventing antibiotic-associated diarrhea.

References

  1. (). Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Database of Systematic Reviews. DOI
  2. (). Clinical trial: Lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome. World Journal of Gastroenterology. DOI