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Shatavari Side Effects & Safety

Evidence:Emerging
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This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

Safety Profile

Overall safety rating: Generally Safe

Potential Side Effects

  • Generally well-tolerated
  • Mild digestive discomfort in some individuals
  • Allergic reactions in people sensitive to asparagus family plants
  • May cause weight gain with long-term use (anecdotal)
  • Possible diuretic effect

Drug & Supplement Interactions

  • May interact with estrogen-sensitive conditions (phytoestrogenic activity)
  • May enhance effects of diuretic medications
  • May lower blood sugar — monitor with diabetes medications
  • May interact with lithium (diuretic effect could affect lithium levels)
  • Avoid with hormone-sensitive cancers until more research is available

Maximum Dose

Do not exceed: 2000mg extract daily

References

  1. ReviewAlok S, Jain SK, Verma A, Kumar M, Mahor A, Sabharwal M (2013). Plant profile, phytochemistry and pharmacology of Asparagus racemosus (Shatavari): A review. Asian Pacific Journal of Tropical Disease. DOI
  2. AnimalGautam M, Saha S, Bani S, et al. (2009). Immunomodulatory activity of Asparagus racemosus on systemic Th1/Th2 immunity. Journal of Ethnopharmacology. DOI PubMed
  3. RCTPingali U, Nutalapati C, Wang Y (2025). Ashwagandha and Shatavari Extracts Dose-Dependently Reduce Menopause Symptoms, Vascular Dysfunction, and Bone Resorption in Postmenopausal Women: A Randomized, Double-Blind, Placebo-Controlled Study.. Journal of menopausal medicine. DOI PubMed
  4. RCTO'Leary MF, Jackman SR, Bowtell JL (2024). Shatavari supplementation in postmenopausal women alters the skeletal muscle proteome and pathways involved in training adaptation.. European journal of nutrition. DOI PubMed
  5. RCTGreed E, Pritchard J, Struszczak L, Bozbaş E, et al. (2024). Shatavari supplementation during eight weeks of resistance training increases training load, enhances skeletal muscle contractility and alters the skeletal muscle proteome in older women.. Frontiers in nutrition. DOI PubMed
  6. RCTO'Leary MF, Jackman SR, Sabou VR, Campbell MI, et al. (2021). Shatavari Supplementation in Postmenopausal Women Improves Handgrip Strength and Increases Vastus lateralis Myosin Regulatory Light Chain Phosphorylation but Does Not Alter Markers of Bone Turnover.. Nutrients. DOI PubMed