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Slippery Elm Side Effects & Safety

Evidence:Preliminary
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This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

Safety Profile

Overall safety rating: Generally Safe

Potential Side Effects

  • Very well tolerated with a long safety history
  • May slow absorption of oral medications due to mucilage coating
  • Rare allergic reactions in elm-sensitive individuals

Drug & Supplement Interactions

  • All oral medications — take 1-2 hours apart; mucilage may delay drug absorption
  • No known serious drug interactions

Maximum Dose

Do not exceed: No established upper limit; traditional use up to 3,000mg/day

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References

  1. Watts CR, Rousseau B. (2012). Slippery elm, its biochemistry, and use as a complementary and alternative treatment for laryngeal irritation. Journal of Investigational Biochemistry.
  2. ObservationalLangmead L, Dawson C, Hawkins C, et al. (2002). Antioxidant effects of herbal therapies used by patients with inflammatory bowel disease. Alimentary Pharmacology & Therapeutics. DOI PubMed
  3. RCTTinsley G, Urbina S, Santos E, Villa K, et al. (2019). A Purported Detoxification Supplement Does Not Improve Body Composition, Waist Circumference, Blood Markers, or Gastrointestinal Symptoms in Healthy Adult Females.. Journal of dietary supplements. DOI PubMed