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White Willow Bark Dosage Guide

Evidence:Moderate
·

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

120-240mg salicin daily from standardized willow bark extract

Maximum dose: 240mg salicin daily is the maximum studied dose; do not exceed without medical supervision

Dosage Recommendations

General recommendation: 120-240mg salicin daily from standardized willow bark extract

Timing: Take in 2 divided doses with meals; allow 1-2 weeks for full anti-inflammatory effect • Take with food for best absorption.

Dosage by Condition

Lower back pain
240mg salicin dailyModerate
Osteoarthritis
240mg salicin dailyModerate
General pain relief
120-240mg salicin dailyEmerging

Upper limit: 240mg salicin daily is the maximum studied dose; do not exceed without medical supervision

Timing & Absorption

Take in 2 divided doses with meals; allow 1-2 weeks for full anti-inflammatory effect

Best taken with food for optimal absorption.

References

  1. RCTChrubasik S, Eisenberg E, Balan E, et al. (2000). Treatment of low back pain exacerbations with willow bark extract: a randomized double-blind study. American Journal of Medicine. DOI PubMed
  2. RCTSchmid B, Lüdtke R, Selbmann HK, et al. (2001). Efficacy and tolerability of a standardized willow bark extract in patients with osteoarthritis: randomized placebo-controlled, double blind clinical trial. Phytotherapy Research. DOI PubMed
  3. ReviewVlachojannis JE, Cameron M, Chrubasik S (2009). A systematic review on the effectiveness of willow bark for musculoskeletal pain. Phytotherapy Research. DOI PubMed
  4. RCTEvans M, Sulley AM, Crowley DC, Langston J, et al. (2020). Pain Bloc-R Alleviates Unresolved, Non-Pathological Aches and Discomfort in Healthy Adults-A Randomized, Double-Blind, Placebo-Controlled, Crossover Study.. Nutrients. DOI PubMed
  5. RCTNieman DC, Shanely RA, Luo B, Dew D, et al. (2013). A commercialized dietary supplement alleviates joint pain in community adults: a double-blind, placebo-controlled community trial.. Nutrition journal. DOI PubMed