Four Sigmatic Dark Roast Organic Whole Bean Coffee | Gourmet Nootropic Mushroom Coffee Beans with Lion's Mane & Chaga Mushrooms for Enhanced Brain Function and Immune Support | 12oz
$1.60/serving
Price verified Apr 22, 2026
Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use
Our verdict
250mg Lion's Mane + 250mg Chaga fruiting body per serving of Lion's Mane + Chaga per whole bean from Four Sigmatic. Best for home-espresso and French-press enthusiasts who grind their…
Why we recommend this
The freshest format available for mushroom coffee — grinding right before brewing preserves mushroom compound integrity and coffee oils. At 4.6 stars across 886 reviews, taste and quality are strongly validated.
Check for interactions
Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.
Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.
What to watch out for
Whole-bean format requires a grinder, which is a barrier for users without one. Infused mushroom compounds can slightly clog cheaper blade grinders.
Dose & form
- Serving
- 250mg Lion's Mane + 250mg Chaga fruiting body per serving
- Form
- Whole Bean
- Clinical range
- 1-2 cups daily (250-1500mg mushroom extract per serving)
- Dose adequacy
- Therapeutic
- Supply
- 12 servings · $1.60/serving
- UPC
- 816897023141
Who it's best for
Home-espresso and French-press enthusiasts who grind their own beans for maximum freshness
Who should skip it
Drinkers without a grinder or who prefer the convenience of pre-ground or pods
Pros
- Whole bean — grind fresh for peak aroma and extraction
- 250mg each Lion's Mane + Chaga fruiting body per serving
- Single-origin Marcala Honduras, Fair Trade certified
- 4.6 star rating — highest in the Four Sigmatic lineup
Cons
- Requires a burr grinder for optimal extraction
- Only 2 mushroom species (vs Calm's 5-adaptogen blend)
- Higher price than conventional whole-bean organic coffee
What customers say
4.6★ across 886 Amazon reviews. The most common questions from shoppers: re any potential interactions with medications, re any side effects from long-term use, and cause any digestive issues or side effects. Full answers in the FAQ below.
Frequently Asked Questions
What is the clinical dose for Lion's Mane + Chaga?
What is the clinical dose for Lion's Mane + Chaga?
Clinical trials typically use 1-2 cups daily (250-1500mg mushroom extract per serving). Four Sigmatic Dark Roast Whole Bean delivers 250mg Lion's Mane + 250mg Chaga fruiting body per serving, which we classify as Therapeutic relative to that range.
How does Four Sigmatic Dark Roast Whole Bean compare to similar Whole Bean?
How does Four Sigmatic Dark Roast Whole Bean compare to similar Whole Bean?
See the "Also consider" section below for two alternatives. Choose based on form preference (Whole Bean vs alternatives), dose adequacy, and third-party testing.
Is Four Sigmatic Dark Roast Whole Bean third-party tested?
Is Four Sigmatic Dark Roast Whole Bean third-party tested?
Yes — USDA Organic, Fair Trade. Third-party testing verifies ingredient identity and label accuracy.
Does this work with Amazon Subscribe & Save?
Does this work with Amazon Subscribe & Save?
Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.
Are there any potential interactions with medications?
Are there any potential interactions with medications?
Lion's Mane may mildly affect blood sugar and blood clotting — consult your doctor if on diabetes medications or anticoagulants. Chaga has moderate interaction potential with blood thinners due to natural anticoagulant compounds. The 142mg caffeine per serving is standard drip-coffee strength.
Are there any side effects from long-term use?
Are there any side effects from long-term use?
Lion's Mane and Chaga at 250mg food-dose levels are well tolerated long-term per clinical data up to 16 weeks. Chaga's oxalate content can increase kidney stone risk in susceptible individuals over years of heavy daily use. Standard caffeine hygiene applies.
Does it cause any digestive issues or side effects?
Does it cause any digestive issues or side effects?
Fruiting-body mushrooms are easy on digestion — no grain-based mycelium fillers. Freshly ground coffee has more aromatic oils, which some sensitive stomachs react to (bloating, mild acidity). Most users tolerate daily use without issues after a short adjustment.
Can it be taken with other supplements or vitamins?
Can it be taken with other supplements or vitamins?
Yes — works with most daily supplements. Avoid other caffeine sources same day. Tannins in coffee can mildly reduce iron and calcium absorption; take those supplements at least 1 hour away from your coffee window.
Are there any specific instructions for taking it safely?
Are there any specific instructions for taking it safely?
Grind just before brewing for peak freshness — medium grind for drip, coarser for French press, finer for espresso. Use 2 tbsp per 6 oz water. Avoid within 6 hours of bedtime due to caffeine content.
How long until benefits are typically experienced?
How long until benefits are typically experienced?
Caffeine alertness is immediate. Lion's Mane cognitive benefits build over 2-4 weeks at 250-1000mg daily per clinical research. Chaga's antioxidant support is cumulative over weeks of consistent intake.
Also consider
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