Integrative Therapeutics Alpha-Glycosyl Isoquercitrin - Quercetin Supplement for Cell Health & Antioxidant Pathway Support* - Supports Cell Integrity* - Vegan & Dairy-Free - 60 Count (60 Servings)

Clinical trials typically use 500-1000mg daily. Integrative Therapeutics Alpha-Glycosyl Isoquercitrin delivers 1 capsule daily (60 capsules, 60 servings), which we classify as Blend relative to that range.

See the "Also consider" section below for two alternatives. Choose based on form preference (Capsule vs alternatives), dose adequacy, and third-party testing.

Yes — GMP Certified. Third-party testing verifies ingredient identity and label accuracy.

Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.

Quercetin has demonstrated inhibition of certain cytochrome P450 enzymes (particularly CYP3A4 and CYP2C8) in research, which could affect the metabolism of drugs including cyclosporine, statins, and some chemotherapeutic agents — consult your prescriber if you take any of these. Quercetin may also modestly reduce platelet aggregation, which matters if you are on anticoagulants. The enhanced bioavailability of alpha-glycosyl isoquercitrin means interaction potential should be considered at lower milligram doses than standard quercetin.

Quercetin has a strong safety record at dietary and supplemental doses, with clinical studies up to 1000mg/day showing no significant adverse effects. Long-term alpha-glycosyl isoquercitrin use has been assessed in safety studies, with no emerging toxicity concerns at supplemental doses. As with any polyphenol, very high prolonged doses are not well characterized — standard supplemental doses are appropriate for long-term use.

Alpha-glycosyl isoquercitrin is generally well tolerated with minimal GI side effects in published studies. The improved water solubility of this form compared to standard quercetin actually reduces the potential for undissolved quercetin particles causing gut irritation. A small number of quercetin users report mild headache or tingling at high doses — uncommon at the single-capsule dose.

Yes — quercetin pairs well with vitamin C (ascorbic acid), which supports quercetin's antioxidant activity and may enhance bioavailability further. It is compatible with zinc, which has synergistic antioxidant and immune support properties. Avoid combining with bromelain if you have a pineapple or latex allergy, as some quercetin formulas pair these two compounds.

Take 1 capsule daily with or without food. Individuals taking prescription medications metabolized by CYP3A4 should consult their healthcare provider before use due to quercetin's potential enzyme inhibition. Pregnant or breastfeeding women should consult their OB or midwife, as the safety data for quercetin supplementation in pregnancy is limited.

Antioxidant pathway support from quercetin is a cumulative process rather than an acute effect — plasma quercetin levels stabilize within days of daily use, but cellular and antioxidant benefits accrue over 4–8 weeks. Alpha-glycosyl isoquercitrin reaches peak plasma concentration faster than standard quercetin due to superior absorption, which may accelerate the timeline for initial benefits.