Integrative Therapeutics
Integrative Therapeutics formulates practitioner-heritage supplements now widely available to everyday shoppers, with roots tracing to four independent supplement companies founded in the late 1970s and 1980s that were unified in a 2000 merger (company-reported); today the brand is part of the Schwabe North America portfolio, which also includes Nature's Way and Enzymatic Therapy. The catalog spans gastrointestinal, cardiometabolic, cognitive, and botanical support formulas - including Cortisol Manager, Theracurmin HP, Berberine, and the Pro-Flora probiotic line - with individually-dosed labeling on most single- and few-ingredient products sampled in this research. Flagship products including Theracurmin HP and Clinical Nutrients HP have independent testing coverage through ConsumerLab.com, and the brand's Lavela WS 1265 delivers Silexan, a pharmaceutical-grade lavender oil extract developed by parent company Schwabe in Germany. With 93 products available to browse, Integrative Therapeutics represents one of the broader clinical-grade catalogs available directly to consumers, including through Amazon.
A practitioner-heritage supplement brand built on individually-dosed formulations and Schwabe's pharmaceutical-grade botanical sourcing, with ConsumerLab-tested flagship products and convenient direct-to-consumer availability including on Amazon.
Integrative Therapeutics suits shoppers who want practitioner-channel formulation heritage without needing a professional account: predecessor companies dating to the late 1970s and 1980s were unified in a 2000 merger (company-reported), and the brand today sits in the Schwabe North America portfolio alongside Nature's Way and Enzymatic Therapy; 93 products are available to browse across categories spanning gastrointestinal, cardiometabolic, cognitive, and botanical support. Shoppers choose the brand for individually-dosed labeling on most single- and few-ingredient products, independent ConsumerLab testing coverage on flagship items like Theracurmin HP and Clinical Nutrients HP, and access to Schwabe's pharmaceutical-grade Silexan lavender-oil extract in Lavela WS 1265 - sourcing not commonly available at this tier elsewhere. Though built around a clinician-first formulation philosophy, products are sold directly to consumers today through the brand's own site, Amazon, and major online retailers, with generally positive customer review volume on flagship SKUs (a popularity signal, not a quality one). No FDA recalls, warning letters, or class-action litigation were identified for the manufacturer as of the research date.
Catalog at a glance
This page covers 93 Integrative Therapeutics products available to browse across 72 categories, making it practical to compare options and cover several supplement needs from one brand.
Why shoppers choose Integrative Therapeutics
Curcumin & Anti-Inflammatory Support
Theracurmin HP delivers a single-ingredient, enhanced-bioavailability curcumin extract with no proprietary blend, and was selected for independent testing in ConsumerLab's turmeric and curcumin supplements review.
See ranked picks in this category →Foundational Multivitamin
Clinical Nutrients HP fully discloses individual vitamin and mineral amounts with no proprietary blend, and was tested and approved through ConsumerLab's voluntary Quality Certification Program.
See ranked picks in this category →Botanical Sleep & Stress Support
Lavela WS 1265 delivers a single-ingredient, 80mg dose of Silexan, a pharmaceutical-grade lavender-oil extract developed and manufactured by parent company Schwabe in Germany.
Who it's best for
Best for
- Buyers who want practitioner-channel formulation heritage - predecessor companies date to the late 1970s and 1980s, unified in a 2000 merger (company-reported) and today part of the Schwabe North America portfolio - paired with individually-dosed, non-blended labeling on most single- and few-ingredient products.
- Buyers interested in Schwabe's pharmaceutical-grade botanical technology, such as the Silexan lavender-oil extract in Lavela WS 1265, not commonly available at this quality tier elsewhere.
- Buyers who value independent-lab testing coverage on flagship products - ConsumerLab has tested or approved Theracurmin HP and Clinical Nutrients HP.
- Buyers who want convenient direct-to-consumer access - despite practitioner-channel roots, products are sold today via the brand's own site, Amazon, and major online retailers with no professional account required.
Good to know before you choose
- You want a brand-wide, currently-active third-party athletic-safety or clean-label certification - the one concrete NSF Certified for Sport claim (2016, five named products) could not be reconfirmed as active via a direct registry check on the research date, and no USP Verified, Informed Sport, IFOS, B Corp, Friend of the Sea, or USDA Organic listing was found for this brand.
- You want a public, searchable Certificate-of-Analysis library - this brand uses a request/lot-number lookup model rather than a published COA portal.
- You're evaluating Cortisol Manager specifically for its stress/cortisol claims - the strongest independently verified evidence is a published trial of its Relora (magnolia/phellodendron) component tested alone, not the finished 5-ingredient product, and a second widely-cited ashwagandha extract study could not be located in PubMed/MEDLINE.
- You want every product individually dosed with zero proprietary blends - 2 of the 9 products sampled in this research (Cortisol Manager, Pro-Biome) use named proprietary blends rather than fully broken-out per-ingredient amounts.
Pricing & value
Pricing sits at the premium, practitioner-channel-typical tier - one independent comparison source places it alongside Thorne, Pure Encapsulations, and Designs for Health with 'modest' differences among them. This reflects clinician-channel formulation and sourcing choices rather than mass-market economics.
- Cortisol Manager: $26.75 for 30 count / $70.75 for 90 count (observed 2026-07-03, brand-direct pricing)
- Theracurmin HP: $56.00 for 60 count / $93.50 for 120 count (observed 2026-07-03, brand-direct pricing)
- Clinical Nutrients HP: $29.00 for 60 count / $54.50 for 120 count (observed 2026-07-03, brand-direct pricing)
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Explore products from Integrative Therapeutics
Browse all available products below — filter by category to narrow the list.
Browse Products
More categories (60)
Integrative Therapeutics Cortisol Manager
2 tablets per serving, 15 servings per bottle (taken as directed, typically at bedtime) per tablet · Ashwagandha (KSM-66 or equivalent) and L-theanine
Cortisol Manager is Integrative Therapeutics' flagship stress-and-sleep formula, combining ashwagandha and L-theanine — two of the most rigorously studied adaptogens and amino acids for cortisol modulation and relaxation — into a single clinical-grade tablet. Named best overall ashwagandha supplement by Vogue, it addresses the root mechanism of stress-disrupted sleep: elevated evening cortisol that prevents winding down. With 10,315 Amazon reviews and a 4.3-star rating, it is one of the most reviewed and validated practitioner-brand supplements in the stress-support category. Integrative Therapeutics has produced GMP-certified, clinician-trusted supplements since 1979.
Integrative Therapeutics Active B-Complex
2 capsules per serving (60 capsules, 30 servings) per capsule · Active B2, B6, B12 + Methylfolate + Choline
Clinical-grade active B-complex featuring methylated and coenzyme forms of B2, B6, B12, plus choline and methylfolate. Supports cellular energy, neurotransmitter synthesis, and immune function. Gluten-free and dairy-free.
Integrative Therapeutics Berberine
Berberine per capsule (60 capsules, 60 servings) per capsule · Berberine HCl
Practitioner-trusted berberine supplement for metabolic support, providing clinically-studied berberine HCl in a clean, allergen-free capsule free of wheat, gluten, corn, soy, dairy, and artificial additives. GMP certified by Integrative Therapeutics since 1979.
Integrative Therapeutics Theracurmin HP
Theracurmin per serving (60 capsules, 30 servings) per capsule · Theracurmin (Bioavailable Curcumin Complex)
Clinically-studied bioavailable curcumin supplement using Theracurmin technology for 27x greater absorption than standard curcumin extract. Supports post-workout muscle recovery, cardiovascular function, and joint health in a dairy-free, gluten-free capsule.
IT Tri-Magnesium Triple-Form Capsules (90ct)
1 capsule per serving; 90 servings per 90-count bottle per capsule · Tri-Magnesium complex (multiple magnesium forms)
90-capsule tri-form magnesium complex with 2,394 reviews at 4.7 stars, supporting cellular energy, stress response, nerve function, bone, and heart health.
IT Buffered Vitamin C 1000mg Capsules (60ct)
1000mg vitamin C (buffered) per capsule; 1 capsule daily per capsule · Buffered Vitamin C 1000mg per capsule
60 capsules of buffered vitamin C (1000mg per capsule) for immune support, collagen, and antioxidant protection. 2,146 reviews at 4.8 stars. Vegan, gluten-free.
Integrative Therapeutics Lavela WS 1265
1 softgel per serving, 60 servings per softgel · Silexan (oral lavender essential oil, WS 1265)
Clinically studied Silexan oral lavender essential oil shown to reduce anxiety and improve sleep quality without sedation or dependency risk.
Integrative Therapeutics Cortisol Manager Allergen Free
2 capsules per serving; 15 servings per 30-capsule bottle per capsule · Ashwagandha + L-Theanine + Phosphatidylserine
Allergen-free adrenal support capsule combining ashwagandha (Withania somnifera) with L-theanine and phosphatidylserine to support healthy cortisol balance, stress response, and restful sleep. Vegan, gluten-free, dairy-free, and free of all top-9 US allergens. 30 capsules per bottle (15 servings). GMP-manufactured by Integrative Therapeutics since 1979.
IT L-Theanine 200mg Stress Capsules (60ct / 30srv)
200mg L-Theanine per serving (2 capsules); 30 servings per 60-count bottle per capsule · L-Theanine 200mg per serving (100mg per capsule)
60 capsules delivering 200mg L-Theanine per 2-capsule serving for stress response, relaxation, and calm focus support. 1,534 reviews at 4.6 stars. Vegan, gluten-free.
IT NAC N-Acetyl L-Cysteine Capsules (60ct)
1 capsule per serving; dose per capsule not specified in Amazon listing per capsule · N-Acetyl L-Cysteine (NAC)
60 capsules of N-Acetyl L-Cysteine (NAC) for glutathione precursor, respiratory health, and antioxidant support. 1,463 reviews at 4.7 stars. Gluten-free, dairy-free.
Integrative Therapeutics Activated Charcoal
2 capsules per serving, 50 servings per capsule · Activated Charcoal (coconut husk)
Coconut husk-sourced activated charcoal in clinical-grade capsules to adsorb and eliminate unwanted gut substances and support digestive wellness.
Integrative Therapeutics HPA Adapt
1 capsule per serving (120 capsules, 120 servings per bottle) per capsule · Sensoril Ashwagandha + Rhodiola Root Extract + Eleuthero + Maca + Holy Basil
Clinical-grade multi-adaptogen formula combining Sensoril ashwagandha, rhodiola, eleuthero, maca, and holy basil to support HPA axis function, healthy stress hormone balance, and a calm, positive stress response. Vegan, gluten-free, and dairy-free.
IT Lipase Concentrate-HP (90ct / 45 Servings)
2 capsules per serving; 45 servings per 90-count bottle per capsule · Lipase (microbial, high-potency concentrate)
pH-stable lipase enzyme concentrate for fat digestion and GI tract support, active in both acid and alkaline conditions. 90 capsules, 45 servings, dairy-free and vegan.
Integrative Therapeutics Zinc-Carnosine
75 mg zinc-carnosine (delivering 16 mg elemental zinc) per capsule per capsule · PepZinGI (Zinc-Carnosine Complex)
Patented PepZinGI zinc-carnosine complex delivering 16 mg zinc per capsule for GI mucosal support. Vegan, gluten-free, no animal ingredients.
IT DHEA-5 5mg Capsules (60ct)
5mg DHEA per capsule; 1 capsule daily per capsule · DHEA (dehydroepiandrosterone) 5mg
5mg DHEA capsules supporting healthy aging and adrenal hormone balance, with 952 reviews. Vegan, gluten-free, and dairy-free from Integrative Therapeutics.
Integrative Therapeutics Liquid Calcium Magnesium
1 tablespoon (15 mL) once daily with food (32 servings per 16 oz bottle) per liquid · Calcium Citrate + Magnesium Citrate + Vitamin D (400 IU)
Liquid calcium-magnesium supplement in a 2:1 citrate ratio with 400 IU vitamin D per serving. Orange vanilla flavored, sugar-free, gluten-free, and dairy-free. Designed for bone health support and easy daily compliance.
IT Similase Digestive Enzymes
2 capsules per serving (90 capsules, 45 servings) per capsule · Microbial-source digestive enzyme blend
Vegan microbial digestive enzyme blend active across a broad pH range to support digestion and nutrient assimilation. Dairy-free, 90 capsules (45 servings).
Integrative Therapeutics Similase GFCF
Microbial enzyme blend per 2-capsule serving (120 capsules, 60 servings) per capsule · DPP IV-Active Microbial Enzyme Blend (Protease with DPP IV Activity)
Clinical-grade digestive enzyme capsule formulated specifically to support dipeptidyl peptidase IV (DPP IV) activity for digestion of proline-containing dipeptides from gluten and casein. Vegan, dairy-free, and designed for adults with GFCF sensitivity.
IT Liquid Calcium Magnesium Berry
Calcium and magnesium in 1:1 ratio per 15 mL serving with vitamin D3 per liquid · Calcium + Magnesium (1:1 ratio) + Vitamin D3
Berry-flavoured liquid delivering a 1:1 calcium-to-magnesium ratio plus vitamin D3 for bone support. Sugar-free, gluten-free, dairy-free. 32 servings per bottle.
IT Pro-Flora Women's Probiotic 30ct
1 capsule per serving (30 servings per bottle) per capsule · Lactobacillus rhamnosus GR-1 + Lactobacillus reuteri RC-14
Shelf-stable women's probiotic with clinically studied Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 for urogenital health.
Integrative Therapeutics Riboflavin B2 Vitamin
Riboflavin (B2) per tablet (30 tablets, 30 servings at 1 tablet/day); product weight listed as 400 mg per tablet per tablet · Riboflavin (Vitamin B2)
Clinical-grade riboflavin (vitamin B2) tablet from Integrative Therapeutics supporting cellular energy, red blood cell production, and enzymatic cofactors. Vegan, gluten-free.
IT Vitamin D3 125 mcg Chewable
125 mcg (5,000 IU) vitamin D3 per chewable tablet (90 tablets, 90 servings) per chewable tablet · Vitamin D3 (cholecalciferol) 5,000 IU
High-potency 5,000 IU (125 mcg) vitamin D3 as cholecalciferol in a chocolate-flavored chewable tablet. Supports calcium absorption, bone health, and immune function. Gluten-free, dairy-free, sugar-free. Clinical-grade Integrative Therapeutics formulation.
Integrative Therapeutics Probiotic Pearls
Probiotic blend per pearl capsule (30 count, 30 servings at 1 capsule/day) per capsule · Probiotic Blend (Lactobacillus + Bifidobacterium)
Clinical-grade pearl-form probiotic from Integrative Therapeutics with Lactobacillus and Bifidobacterium for daily gut and immune support. Soy-free.
IT B12-Active Methylcobalamin Chewable
1 chewable tablet per serving, methylcobalamin form (30 tablets, 30 servings) per chewable · Methylcobalamin (active B12)
Methylcobalamin B12 cherry chewable using the active bioavailable form requiring no body conversion. Gluten-free, soy-free, dairy-free. 30 tablets.
Quality & transparency details
Individually-dosed label transparency (sampled)
Product lineLabel-documentedDirectly reading 9 sampled product labels across categories (omega-3, curcumin, multivitamin, berberine, amino acid, B-vitamin, probiotic, botanical), 7 fully disclose individual ingredient amounts with no proprietary blend: Pure Omega Liquid, Theracurmin HP, Clinical Nutrients HP, Berberine, GABA, Active B-Complex, and Lavela WS 1265. The other 2 (Cortisol Manager, Pro-Biome) each contain one or two named proprietary blends. This reflects a 9-product sample, not a catalog-wide audit.
Independent testing coverage on flagship products
Specific productsIndependently documentedConsumerLab.com, an independent supplement-testing organization, has evaluated at least 2 products: Theracurmin HP was included in a ConsumerLab curcumin-category review, and Clinical Nutrients HP was tested and approved through ConsumerLab's voluntary Quality Certification Program. This coverage is scoped to these 2 named products, not the full catalog.
Manufacturing and laboratory certifications (company-reported)
Facility-specificCompany-reportedThe company states its Green Bay, WI manufacturing facility holds third-party 'Drug Good Manufacturing Practices' certification beyond standard dietary-supplement GMP, and that its onsite lab earned ISO/IEC 17025 accreditation in 2021. Neither claim names an accrediting body, and neither was confirmed against a public registry in this research; treat both as company-reported pending independent confirmation.
Per-lot quality testing (available by request)
Brand-wideAvailable by requestThe company describes vendor/facility audits and per-lot raw-material and finished-goods testing; for at least one product (Pure Omega Liquid), results are described as available to customers using the lot number printed on the bottle, rather than through a searchable public COA database. No public COA library was located for this brand as of the research date.
Our evaluation criteria
ConsumerLab has evaluated 2 named products (Theracurmin HP, Clinical Nutrients HP); a 2016 NSF Certified for Sport claim covering 5 named products could not be reconfirmed via a live registry check on 2026-07-03.
2 of 9 sampled products (Cortisol Manager, Pro-Biome) use named proprietary blends; the other 7 sampled products (Pure Omega Liquid, Theracurmin HP, Clinical Nutrients HP, Berberine, GABA, Active B-Complex, Lavela WS 1265) are fully individually dosed.
Sampled products list individually labeled doses (e.g., Theracurmin HP 600mg curcumin, GABA 750mg, Berberine 500mg); a systematic per-product literature-dose match was outside this research's scope.
Per-lot test results are available by request via lot number (e.g., Pure Omega Liquid); no searchable public COA database was located as of 2026-07-03.
What to check before buying
Certificates of Analysis are request-based, not published
Per-lot testing is described on the company's Quality page and at least one product page (Pure Omega Liquid), but results are provided to customers by request via lot number rather than through a searchable public COA database, as of 2026-07-03.
Cortisol Manager's headline evidence is ingredient-level
The strongest published evidence behind Cortisol Manager's stress/cortisol positioning is a peer-reviewed, PubMed-indexed trial (PMID 23924268) of its Relora (magnolia/phellodendron) component tested alone - not the finished 5-ingredient product. A separate, widely-cited 2008 study on Sensoril-brand ashwagandha (the product's other primary active ingredient) could not be located in PubMed/MEDLINE in this research and should be treated as company-reported/marketing-referenced, never as independently verified peer-reviewed evidence.
Proprietary blends appear in 2 of 9 sampled products
Cortisol Manager (two named proprietary blends) and Pro-Biome (one 10-strain proprietary probiotic blend) do not fully break out individual per-ingredient or per-strain amounts, unlike the 7 other sampled products, which were fully individually dosed.
What this research does not establish
- This research could not reconfirm the brand's historical (January 2016) NSF Certified for Sport claim covering five named products as currently active: a live registry check on 2026-07-03 returned no matching listings. Whether the certification lapsed, was discontinued after reformulation, or reflects a registry search limitation could not be determined - treat as needs-reverification, not a current certification.
- Label-transparency and dosing findings are based on a 9-product sample selected for category diversity, not randomly drawn from the brand's full catalog, and should not be generalized brand-wide.
- Several sources could not be directly rendered in this research pass: consumerlab.com and reviewmeta.com returned HTTP 403, dietspotlight.com failed SSL handshake, and naturalmedicinejournal.com failed DNS resolution. Findings drawn from these areas rely on search-engine snippet synthesis rather than directly rendered pages.
- ISO/IEC 17025 laboratory accreditation (claimed 2021) and 'Drug Good Manufacturing Practices' facility certification are specific and plausible but rest entirely on company-reported text; no named accrediting body was identified or independently confirmed against a public registry.
- No single founding year could be independently verified for the unified entity: the brand's own materials use at least three different heritage-length framings (a current homepage claim of 'over 25 years,' other brand-profile pages describing 'more than 35 years,' and four different predecessor-company founding years from 1975-1987), with no source confirming one exact founding date.
Research last updated: 2026-07-03
Sources
Integrative Therapeutics, LLC's parent company is Schwabe North America, Inc.
Company · Accessed 2026-07-03 · Corroborated independently by New Hope Network trade press (see companion source below).
- 2.New Hope Network - "Schwabe North America acquires Wellesse brand"Brand-wideIndependently documented
Schwabe North America's brand portfolio comprises three heritage brands: Nature's Way, Enzymatic Therapy, and Integrative Therapeutics.
Press · Accessed 2026-07-03 · Independent trade press dated March 13, 2013; resolves the ownership question independently of the brand's own materials and refutes a Nestle Health Science ownership hypothesis.
- 3.New Hope Network - "Schwabe North America acquires Wellesse brand"Brand-wideIndependently documented
Dr. Willmar Schwabe, Schwabe North America's German parent, is a pharmaceutical/herbal-medicine company founded in 1866, headquartered in Karlsruhe, Germany, operating in 60+ countries.
Press · Accessed 2026-07-03
Integrative Therapeutics LLC was formed in 2000 through the merger of four previously independent companies: Vitaline Formulas (1975), NF Formulas (1978), PhytoPharmica (1981), and Tyler Encapsulations (1987).
Company · Accessed 2026-07-03 · Individual 1975/1978/1981/1987 founding years were not independently cross-checked against a non-brand-controlled source.
- 5.SupplySide SJ - "Integrative Therapeutics Acquires Vitaline Corp."Brand-wideIndependently documented
In October 2000, Integrative Therapeutics acquired Vitaline Corp. in a deal backed by North Castle Partners, becoming the umbrella parent for four predecessor brands.
Press · Accessed 2026-07-03 · Independent trade-press report, not brand-controlled; corroborates the 2000 unification date without confirming a single earlier founding year.
- 6.Integrative Therapeutics homepage vs. Natural Practitioner Magazine / NDNR brand profilesBrand-wideLimited public information
The brand's own 'years of heritage' claims are inconsistent (over 25 years per the current homepage vs. more than 35 years per other brand-profile pages), with no source confirming a single specific founding year.
Other · Accessed 2026-07-03 · No source independently confirms one specific founding year for the unified entity; a single hard founding-year claim is not supportable from public sources.
Integrative Therapeutics markets itself as 'clinician-curated,' positioning products as curated by practitioners, for practitioners.
Company · Accessed 2026-07-03
- 8.Solutions4Health - "The Ultimate Guide to the Best Supplement Brands"Brand-wideIndependently documented
An independent comparison source groups Integrative Therapeutics with Thorne, Pure Encapsulations, and Designs for Health as peer premium practitioner-channel brands, describing price differences among them as 'modest.'
Other · Accessed 2026-07-03 · One reviewer's qualitative framing, not an audited benchmark; its GMP-facility language echoes the brand's own FAQ, so it may not be fully independent of brand messaging.
Integrative Therapeutics products are sold direct-to-consumer through the brand's own official Amazon storefront and third-party retailers (PureFormulas, Natural Healthy Concepts, Vitacost).
Retailer · Accessed 2026-07-03
- 10.Professional Supplement Center blog - "NSF Certified for Sport from Integrative Therapeutics"Product lineIndependently documented
In January 2016, five named products (Cortisol Manager, Active B Complex, Theracurmin HP, Vasophil, Pure Omega HP) earned NSF Certified for Sport certification.
Press · Accessed 2026-07-03 · Historical announcement; see the registry-check source for current-status findings.
A direct, live NSF Certified for Sport registry search for 'Integrative Therapeutics' returned zero matching products on the research date.
Independent certifier · Accessed 2026-07-03 · Does not confirm the 2016 certification never existed - only that it could not be reconfirmed as currently active via direct registry query.
The company states its Green Bay facility holds third-party 'Drug Good Manufacturing Practices' certification, beyond standard dietary-supplement GMP.
Company · Accessed 2026-07-03 · No named accrediting body identified; not confirmed against a public registry in this research.
The company states its onsite lab earned ISO/IEC 17025 accreditation in 2021.
Company · Accessed 2026-07-03 · No named accrediting body (e.g., A2LA, ANAB) identified; not confirmed against a public registry in this research.
- 14.Web search across certifier registries (USP, Informed Sport, IFOS, B Corp, Friend of the Sea, USDA Organic)Brand-wideLimited public information
No USP Verified Mark, Informed Sport/Informed Choice, IFOS, B Corp, Friend of the Sea, or USDA Organic listing was found for any Integrative Therapeutics product or facility.
Other · Accessed 2026-07-03 · Absence established via search, not an exhaustive direct query of every interactive certifier registry.
- 15.Integrative Therapeutics - Quality page; Pure Omega Liquid product pageBrand-wideAvailable by request
The company describes per-lot raw-material and finished-goods testing; for Pure Omega Liquid, results are available to customers by lot number rather than through a public COA database.
Company · Accessed 2026-07-03
- 16.Integrative Therapeutics product pages (Pure Omega Liquid, Theracurmin HP, Clinical Nutrients HP, Berberine, GABA, Active B-Complex, Lavela WS 1265)Product lineLabel-documented
7 of 9 sampled products fully disclose individual ingredient amounts with no proprietary blend.
Company · Accessed 2026-07-03 · Directly fetched and read from each brand-owned product page; a 9-product sample, not exhaustive across the full catalog.
Cortisol Manager's label discloses two named proprietary blends (a 500mg Stress-Reducing blend and a 450mg Cortisol-Reducing blend) alongside a separately-dosed 100mg phosphatidylserine ingredient.
Company · Accessed 2026-07-03
Pro-Biome's label discloses a single 525mg, 10-strain proprietary probiotic blend without individual per-strain CFU counts.
Company · Accessed 2026-07-03
- 19.Integrative Therapeutics product pages (Cortisol Manager, Theracurmin HP, Clinical Nutrients HP)Specific productsCompany-reported
Observed direct-from-brand pricing: Cortisol Manager $26.75/30ct and $70.75/90ct; Theracurmin HP $56.00/60ct and $93.50/120ct; Clinical Nutrients HP $29.00/60ct and $54.50/120ct.
Company · Accessed 2026-07-03 · Brand-direct list prices, point-in-time; practitioner-account and third-party retailer pricing not checked.
ConsumerLab.com has evaluated at least 2 products: Theracurmin HP (curcumin-category review) and Clinical Nutrients HP (tested and approved through its Quality Certification Program).
Independent certifier · Accessed 2026-07-03 · Accessed via search-indexed snippets; direct page fetch returned HTTP 403 in this research session.
Flagship SKUs show substantial, generally positive Amazon review volume (e.g., Active B-Complex ~4.6/5 with 4,460+ ratings; Cortisol Manager ~4.4/5 with 5,000+ ratings).
Retailer · Accessed 2026-07-03 · Popularity/satisfaction evidence only, never a quality or scientific claim.
- 22.PubMed - Talbott et al., "Effect of Magnolia officinalis and Phellodendron amurense (Relora) on cortisol and psychological mood state in moderately stressed subjects"Specific productsIndependently documented
A peer-reviewed, PubMed-indexed trial (PMID 23924268) found the Relora magnolia/phellodendron blend significantly reduced salivary cortisol vs. placebo over 4 weeks - tested as a standalone ingredient blend, not the finished Cortisol Manager product.
Other · Accessed 2026-07-03
A widely-cited 2008 Sensoril-brand ashwagandha study (Auddy et al.) referenced in marketing could not be located in PubMed/MEDLINE under any searched author/keyword combination.
Other · Accessed 2026-07-03 · Must not be cited as peer-reviewed; treat Cortisol Manager's Sensoril-related evidence as company-reported/marketing only, per adjudication.
No FDA warning letter addressed to Integrative Therapeutics was located via targeted search.
Regulator · Accessed 2026-07-03 · Search-based absence check, not an exhaustive direct database query by exact name.
A direct query of the FDA's openFDA enforcement API for 'Integrative Therapeutics' as recalling firm returned zero matching records in both food and drug enforcement databases.
Regulator · Accessed 2026-07-03 · Directly-queried government API negative, stronger than a general search-engine absence; covers only what openFDA has classified/indexed.
- 26.Better Business Bureau directory search; general litigation-database web searchBrand-wideLimited public information
No class-action lawsuit, other civil litigation, or Better Business Bureau profile/rating specific to Integrative Therapeutics, LLC (Green Bay, WI) was located.
Other · Accessed 2026-07-03 · Search-based absence check only, not an exhaustive court-docket or BBB-complaint-level clearance.
Frequently Asked Questions
Who owns Integrative Therapeutics?
Who owns Integrative Therapeutics?
Integrative Therapeutics, LLC is part of Schwabe North America, the U.S. division of German pharmaceutical and herbal-medicine company Dr. Willmar Schwabe. Schwabe North America's portfolio also includes Nature's Way and Enzymatic Therapy.
Do I need to be a healthcare practitioner to buy Integrative Therapeutics products?
Do I need to be a healthcare practitioner to buy Integrative Therapeutics products?
Traditionally, Integrative Therapeutics sold exclusively through licensed healthcare professionals (physicians, naturopaths, functional medicine practitioners). Today, most products are also available through the brand's own site, Amazon, and other third-party retailers without a prescription. The brand still recommends professional supervision for condition-specific products like Cortisol Manager, since dosing and selection decisions can benefit from clinical guidance.
Are Integrative Therapeutics products third-party tested?
Are Integrative Therapeutics products third-party tested?
Coverage varies by product. ConsumerLab.com, an independent testing organization, has evaluated at least two flagship products (Theracurmin HP, Clinical Nutrients HP) - Theracurmin HP in a category review, Clinical Nutrients HP through ConsumerLab's Quality Certification Program. A 2016 NSF Certified for Sport claim covering five named products could not be reconfirmed as currently active in a registry check on 2026-07-03.
How does Cortisol Manager work, and what's the evidence behind it?
How does Cortisol Manager work, and what's the evidence behind it?
Cortisol Manager combines Ashwagandha (Sensoril branded extract), Phosphatidylserine, and L-Theanine. The strongest peer-reviewed evidence is a PubMed-indexed trial of its Relora (magnolia/phellodendron) component tested alone, not the finished 5-ingredient product. A separate, widely-cited 2008 Sensoril-ashwagandha study referenced in marketing could not be located in PubMed/MEDLINE in this research and should be treated as company-reported marketing rather than peer-reviewed evidence.
This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer