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IT Pro-Flora Women's Probiotic 30ct — view 1 of 5
Integrative Therapeutics

Integrative Therapeutics Pro-Flora Women’s Probiotic - Vaginal Health Probiotic - Supports Urogenital Health in Women* - Gluten-Free - 30 Capsules (30 Capsules)

4.2· 829 Amazon reviews
$33.75$32.06with Subscribe & Save

$1.13/serving

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Price verified Apr 22, 2026

Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use

Our verdict

1 capsule per serving (30 servings per bottle) of Lactobacillus rhamnosus GR-1 + Lactobacillus reuteri RC-14 per capsule from Integrative Therapeutics. Best for women seeking targeted urogenital and vaginal flora…

Third-Party TestedGluten-freeNo refrigeration requiredCapsuleSubscribe & Save

Why we recommend this

The Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 combination is backed by more published clinical research for urogenital health than virtually any other probiotic strain combination. For women with recurring vaginal flora imbalances, this targeted formulation from a GMP-certified practitioner brand offers a clinically grounded approach that broad-spectrum gut probiotics cannot replicate.

Check for interactions

Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.

Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.

What to watch out for

Pro-Flora Women's Probiotic has a 4.2-star average across 829 reviews — the lowest average rating among these five products. This suggests a meaningful subset of users did not experience their expected outcomes, possibly reflecting unmet expectations around GI health versus the product's urogenital-specific mechanism. At $33.75 for 30 capsules, ongoing monthly cost is also a consideration.

Dose & form

Serving
1 capsule per serving (30 servings per bottle)
Form
Capsule
Clinical range
≥1 billion CFU of GR-1/RC-14 per day — aligned with clinical trial doses used in published research
Dose adequacy
Therapeutic
Supply
30 servings · $1.13/serving
UPC
871791706712

Who it's best for

Women seeking targeted urogenital and vaginal flora balance with two clinically studied Lactobacillus strains

Who should skip it

General gut health probiotic users — this is formulated specifically for vaginal/urogenital support, not broad GI health

Pros

  • Uses two of the most studied strains for urogenital health: GR-1 and RC-14
  • Shelf-stable — no refrigeration required for consumer convenience
  • Clinically validated strain combination with peer-reviewed research
  • 30-day supply aligns with monthly routine — easy adherence

Cons

  • Only 30 capsules per bottle ($1.13/day) — ongoing cost adds up
  • Targeted for urogenital health only; not a comprehensive gut microbiome product
  • 4.2 star average is the lowest among this batch — some consumer dissatisfaction

What customers say

4.2★ across 829 Amazon reviews. The most common questions from shoppers: re any potential interactions with medications, re any side effects from long-term use, and cause any digestive issues or side effects. Full answers in the FAQ below.

Frequently Asked Questions

What is the clinical dose for Lactobacillus rhamnosus GR-1 + Lactobacillus reuteri RC-14?

Clinical trials typically use ≥1 billion CFU of GR-1/RC-14 per day — aligned with clinical trial doses used in published research. IT Pro-Flora Women's Probiotic 30ct delivers 1 capsule per serving (30 servings per bottle), which we classify as Therapeutic relative to that range.

How does IT Pro-Flora Women's Probiotic 30ct compare to similar Capsule?

See the "Also consider" section below for two alternatives. Choose based on form preference (Capsule vs alternatives), dose adequacy, and third-party testing.

Is IT Pro-Flora Women's Probiotic 30ct third-party tested?

Yes — Third-Party Tested. Third-party testing verifies ingredient identity and label accuracy.

Does this work with Amazon Subscribe & Save?

Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.

Are there any potential interactions with medications?

Probiotic supplements are generally considered safe with most medications. However, immunosuppressed individuals or those on immunosuppressive drugs should consult their healthcare provider before use, as probiotics introduce live organisms. Antibiotics taken concurrently will reduce probiotic viability — separate antibiotic and probiotic dosing by at least 2 hours and continue probiotics after completing an antibiotic course.

Are there any side effects from long-term use?

Long-term use of Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 has been studied in clinical trials of several months duration with a favorable safety profile. Some individuals experience mild bloating or gas in the first 1–2 weeks as the microbiome adjusts; this typically resolves. Long-term use is considered appropriate for ongoing urogenital flora maintenance.

Does it cause any digestive issues or side effects?

The GR-1/RC-14 strain combination is one of the most clinically studied in women's health. Digestive side effects are uncommon and typically limited to mild, transient bloating during the first week of use. The 829 Amazon reviewers averaging 4.2 stars reflect generally positive tolerability, with satisfaction variance more likely related to outcome expectations than adverse effects.

Can it be taken with other supplements or vitamins?

Pro-Flora Women's Probiotic can be combined with prebiotics, vitamin D, cranberry extract, and other women's health supplements. It is designed for use within a broader health protocol and pairs well with comprehensive gut health support when users also want GI benefits — as this product itself is targeted at urogenital flora rather than the full GI microbiome.

Are there any specific instructions for taking it safely?

Take 1 capsule daily, with or without food. Because this product is shelf-stable, no refrigeration is required — a significant convenience advantage for travel. Consistent daily use is important for maintaining urogenital flora balance; sporadic use will produce inconsistent results. Consult a healthcare provider if symptoms persist despite supplementation.

How long until benefits are typically experienced?

Published clinical research on GR-1/RC-14 supplementation shows measurable changes in urogenital Lactobacillus colonization within 4 weeks. Women targeting vaginal flora balance typically report improvements in 2–4 weeks of consistent daily use. Full urogenital health support benefits may take up to 8 weeks to fully establish.

Also consider

As an Amazon Associate, we earn from qualifying purchases. Some links below are affiliate links — this doesn't affect our editorial independence or product ratings. How we evaluate products

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer