Integrative Therapeutics DHEA-5 - Daily Health Supplement for Healthy Aging* - Endocrine Supplement* - Vegan, Dairy-Free & Gluten-Free - 60 Capsules (60 Servings)
$0.17/serving
Price verified Apr 22, 2026
Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use
Our verdict
5mg DHEA per capsule; 1 capsule daily of DHEA (dehydroepiandrosterone) 5mg per capsule from Integrative Therapeutics. Best for adults seeking a low-dose 5mg DHEA supplement for healthy aging and adrenal…
Why we recommend this
With 952 reviews averaging 4.7 stars and a price of just $10.00 for 60 capsules, IT DHEA-5 offers exceptional value. The vegan, gluten-free, and allergen-clean profile reflects Integrative Therapeutics' practitioner-grade manufacturing standards since 1979.
Check for interactions
Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.
Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.
What to watch out for
At 5mg per capsule, this is a conservative dose that may not produce measurable endocrine effects in adults with significant DHEA deficiency. Clinical DHEA protocols typically use 25-100mg daily. This dose is best suited for maintenance or cautious introduction under practitioner supervision.
Dose & form
- Serving
- 5mg DHEA per capsule; 1 capsule daily
- Form
- Capsule
- Clinical range
- DHEA studied at 25-200mg/day for endocrine support; 5mg is a conservative maintenance dose
- Dose adequacy
- Partial
- Supply
- 60 servings · $0.17/serving
- UPC
- 871791000681
Who it's best for
Adults seeking a low-dose 5mg DHEA supplement for healthy aging and adrenal hormone support under practitioner supervision
Who should skip it
Those needing higher DHEA replacement doses — this is a conservative 5mg entry-level dose, not a therapeutic replacement level
Pros
- Low 5mg dose — appropriate for conservative DHEA entry or maintenance
- 952 reviews at 4.7 stars — strong social proof for a practitioner-grade hormone product
- Vegan, gluten-free, dairy-free — clean allergen profile
- 60 servings at $10.00 — excellent value per dose
Cons
- 5mg dose is well below clinical DHEA study doses (25-200mg) — may be subtherapeutic for deficiency
- DHEA is a hormone precursor — not appropriate without practitioner assessment of baseline levels
- Should not be used by those with hormone-sensitive conditions without medical guidance
What customers say
4.7★ across 952 Amazon reviews. The most common questions from shoppers: re any potential interactions with medications, re any side effects from long-term use, and cause any digestive issues or side effects. Full answers in the FAQ below.
Frequently Asked Questions
What is the clinical dose for DHEA (dehydroepiandrosterone) 5mg?
What is the clinical dose for DHEA (dehydroepiandrosterone) 5mg?
Clinical trials typically use DHEA studied at 25-200mg/day for endocrine support; 5mg is a conservative maintenance dose. IT DHEA-5 5mg Capsules (60ct) delivers 5mg DHEA per capsule; 1 capsule daily, which we classify as Partial relative to that range.
How does IT DHEA-5 5mg Capsules (60ct) compare to similar Capsule?
How does IT DHEA-5 5mg Capsules (60ct) compare to similar Capsule?
See the "Also consider" section below for two alternatives. Choose based on form preference (Capsule vs alternatives), dose adequacy, and third-party testing.
Is IT DHEA-5 5mg Capsules (60ct) third-party tested?
Is IT DHEA-5 5mg Capsules (60ct) third-party tested?
Yes — GMP Certified. Third-party testing verifies ingredient identity and label accuracy.
Does this work with Amazon Subscribe & Save?
Does this work with Amazon Subscribe & Save?
Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.
Are there any potential interactions with medications?
Are there any potential interactions with medications?
DHEA can interact with hormone-sensitive medications including estrogens, androgens, corticosteroids, and insulin. Those with hormone-sensitive cancers, thyroid conditions, or polycystic ovary syndrome (PCOS) should consult their physician before use. DHEA affects androgen and estrogen pathways.
Are there any side effects from long-term use?
Are there any side effects from long-term use?
At 5mg/day, DHEA is generally well tolerated for most adults. Higher doses can cause acne, hair loss, mood changes, and hormonal imbalance over time. Long-term use at any dose warrants periodic monitoring of DHEA-S serum levels with a practitioner.
Does it cause any digestive issues or side effects?
Does it cause any digestive issues or side effects?
DHEA at 5mg is unlikely to cause digestive issues. Hormonal side effects (acne, oily skin, irritability) are more relevant than GI concerns. Taking with food is optional but can reduce any mild stomach sensitivity in susceptible individuals.
Can it be taken with other supplements or vitamins?
Can it be taken with other supplements or vitamins?
DHEA can be taken alongside standard vitamins and minerals without direct conflicts. Avoid stacking with other hormone-modulating supplements (pregnenolone, 7-keto-DHEA, tribulus) without practitioner guidance, as cumulative hormonal effects can be unpredictable.
Are there any specific instructions for taking it safely?
Are there any specific instructions for taking it safely?
Take 1 capsule daily as directed. Baseline DHEA-S serum level testing is recommended before starting. Not for children. Women who are pregnant or breastfeeding should not use DHEA. Consult a healthcare professional before use if you have any hormone-sensitive condition.
How long until benefits are typically experienced?
How long until benefits are typically experienced?
DHEA supplementation's effects on aging and endocrine support are typically assessed after 8-12 weeks of daily use. Serum DHEA-S levels can be checked at 8 weeks to confirm meaningful supplementation. Subjective effects (energy, mood) may be noticed within 4-6 weeks.
