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Life Extension Ultra Prostate Formula — view 1 of 5
Life Extension

Life Extension Ultra Prostate Formula, Saw Palmetto for Men, pygeum, stinging Nettle Root, lycopene, Prostate Health, Urination Flow, PSA, Non-GMO, Gluten-Free, 60 softgels

4.2· 4,178 Amazon reviews
$26.33$25.01with Subscribe & Save

$0.88/serving

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Price verified Apr 22, 2026

Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use

Our verdict

100mg pygeum + 320mg saw palmetto + beta-sitosterol + nettle root per serving of Pygeum + Saw Palmetto + Beta-Sitosterol + Nettle Root + Lycopene per softgel from Life Extension…

Third-Party TestedGluten-freeNon-GMOSoftgelSubscribe & Save

Why we recommend this

The most comprehensive prostate formula available, combining pygeum, saw palmetto, beta-sitosterol, nettle root, and lycopene — all at clinically relevant doses. Each ingredient targets different mechanisms: 5-alpha-reductase inhibition, anti-inflammatory action, and antioxidant support. Life Extension is known for research-backed formulations.

Check for interactions

Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.

Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.

What to watch out for

Most expensive option. Multi-ingredient formula may not be needed by everyone. Requires 2 softgels per serving.

Dose & form

Serving
100mg pygeum + 320mg saw palmetto + beta-sitosterol + nettle root per serving
Form
Softgel
Clinical range
100-200mg standardized bark extract daily
Dose adequacy
Therapeutic
Supply
30 servings · $0.88/serving
UPC
737870202967

Who it's best for

Most comprehensive prostate support formula

Who should skip it

Budget shoppers or those wanting a simple single-ingredient pygeum.

Pros

  • Most comprehensive prostate formula
  • All ingredients at clinical doses
  • Multiple mechanisms of action
  • Research-driven Life Extension formulation

Cons

  • Premium price ($0.65/serving)
  • Requires 2 softgels per serving
  • May be more than needed for basic support
  • Complex formula

What customers say

4.2★ across 4,178 Amazon reviews. The most common questions from shoppers: life extension ultra prostate formula safe for daily use, i take life extension ultra prostate with prescription medications, and life extension ultra prostate affect testosterone levels. Full answers in the FAQ below.

Frequently Asked Questions

What is the clinical dose for Pygeum + Saw Palmetto + Beta-Sitosterol + Nettle Root + Lycopene?

Clinical trials typically use 100-200mg standardized bark extract daily. Life Extension Ultra Prostate Formula delivers 100mg pygeum + 320mg saw palmetto + beta-sitosterol + nettle root per serving, which we classify as Therapeutic relative to that range.

How does Life Extension Ultra Prostate Formula compare to similar Softgel?

See the "Also consider" section below for two alternatives. Choose based on form preference (Softgel vs alternatives), dose adequacy, and third-party testing.

Is Life Extension Ultra Prostate Formula third-party tested?

Yes — Third-Party Tested. Third-party testing verifies ingredient identity and label accuracy.

Does this work with Amazon Subscribe & Save?

Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.

Is Life Extension Ultra Prostate Formula safe for daily use?

Life Extension Ultra Prostate Formula has a well-established safety profile. Each ingredient (pygeum, saw palmetto, beta-sitosterol, nettle root, lycopene) has individual clinical evidence supporting safety at the doses included. Life Extension products undergo rigorous third-party testing.

Can I take Life Extension Ultra Prostate with prescription medications?

Consult your urologist before combining Ultra Prostate Formula with prescription prostate medications like tamsulosin or finasteride. While the ingredients are natural, they target similar pathways as some prescription drugs, and combining may produce additive effects requiring monitoring.

Does Life Extension Ultra Prostate affect testosterone levels?

Ultra Prostate Formula works primarily at the local prostate tissue level. Saw palmetto and pygeum inhibit 5-alpha-reductase locally, reducing DHT conversion in the prostate without significantly lowering circulating testosterone levels in the bloodstream.

Are there side effects with Life Extension Ultra Prostate Formula?

Ultra Prostate Formula is generally well-tolerated. Uncommon side effects may include mild digestive discomfort or headache. Taking it with food typically prevents GI issues. Serious adverse effects are rare with the botanical and nutrient ingredients in this comprehensive formula.

Is Life Extension Ultra Prostate safe for men over 70?

Yes, Ultra Prostate Formula is commonly used by older men for prostate support. The ingredients have been studied in older populations with favorable safety data. Men over 70 should discuss all supplements with their physician, especially if taking multiple medications.

How many softgels of Life Extension Ultra Prostate should I take daily?

Take 2 softgels per day with a meal. This provides the full clinical doses of all five included ingredients. You can take both softgels at once or split them between meals. The 60-softgel bottle provides a 30-day supply.

Also consider

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This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer