Sports Research Berberine - Herbal Ayurvedic Metabolic Health Support - 1000 mg - 60 Capsules - Vegan Certified, Gluten-Free, Non-GMO

Clinical trials typically use 500mg 2-3x daily with meals (1000-1500mg total). Sports Research Berberine 1000mg (Vegan, 60 Capsules) delivers 1000mg berberine per serving (2 capsules), 60 capsules (30-day supply), which we classify as Therapeutic relative to that range.

See the "Also consider" section below for two alternatives. Choose based on form preference (Capsule vs alternatives), dose adequacy, and third-party testing.

Yes — Yes — Non-GMO tested, Vegan Certified, cGMP-compliant, third-party tested. Third-party testing verifies ingredient identity and label accuracy.

Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.

Berberine has significant drug interactions. It can potentiate blood sugar-lowering medications (metformin, insulin, sulfonylureas), interact with antibiotics such as cyclosporine, and may affect anticoagulant activity. Always consult your physician before starting berberine if you take any chronic medications.

Long-term berberine use is studied in 3 to 6 month trials with generally safe outcomes for metabolic health. Some research suggests potential effects on the gut microbiome with extended use — periodic breaks may be advisable with physician guidance.

GI side effects including cramping, constipation, diarrhea, and nausea are among the most commonly reported with berberine. Starting with a lower dose (one capsule) and gradually increasing may help reduce initial GI discomfort.

Berberine can be stacked with omega-3s, magnesium, or a multivitamin. Avoid combining with other blood sugar-lowering supplements such as chromium or alpha-lipoic acid without physician guidance, as effects may compound.

Take 500mg (one capsule) with meals 2 to 3 times daily, or as directed. Berberine should be taken with food to minimize GI side effects and to support consistent blood levels throughout the day.

Metabolic health benefits — including improvements in fasting blood glucose and lipid levels — are typically observed within 4 to 12 weeks of consistent supplementation at therapeutic doses.