Sports Research® Pure Saffron Supplement, 30 mg - Mood & Stress Support - Made w/Affron® Saffron Extract - Vegan Certified · Non-GMO · Gluten Free – 60 Veggie Softgels

Clinical trials typically use 28-30mg standardized saffron extract daily. Sports Research Pure Saffron 30mg with Affron Extract delivers 30mg Affron Saffron Extract per softgel; 1 softgel daily, which we classify as Therapeutic relative to that range.

See the "Also consider" section below for two alternatives. Choose based on form preference (Softgel vs alternatives), dose adequacy, and third-party testing.

Yes — Vegan Certified, Non-GMO Tested, Gluten-Free, Carrageenan-Free, cGMP (USA). Third-party testing verifies ingredient identity and label accuracy.

Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.

Saffron may potentiate serotonergic activity — avoid combining with SSRIs, SNRIs, MAOIs, or other serotonin-active medications without physician supervision, as serotonin syndrome risk increases when multiple serotonergic agents are combined. Saffron has mild anticoagulant properties; consult your doctor if you take blood thinners. Affron saffron extract has not shown significant CYP enzyme interactions in available pharmacokinetic studies.

Affron saffron extract at 28–30mg/day has been studied in clinical trials up to 8 weeks with an excellent safety profile comparable to placebo in adverse event rates. Traditional saffron consumption as a spice for centuries supports its long-term safety at food and low-supplement doses. Very high doses (above 5g/day of whole saffron) are associated with toxicity, but 30mg extract is far below this threshold.

Saffron at supplemental doses is generally gentle on digestion. A small percentage of users report mild nausea, especially when taken on an empty stomach. The most commonly reported side effect in Affron clinical trials is mild headache in the first week of use, which typically resolves. The veggie softgel format minimizes direct GI contact with the extract.

Saffron pairs well with most daily supplements. It stacks naturally with Ashwagandha for stress support or Magnesium Glycinate for sleep, as these work through complementary pathways. Do not combine with other serotonin-active supplements (5-HTP, St. John's Wort, L-Tryptophan) without medical guidance. Avoid adding additional anticoagulant supplements simultaneously.

Take one softgel daily, preferably with a meal. Not recommended during pregnancy — saffron has traditional emmenagogue properties (stimulates uterine contractions) and is avoided in pregnancy. Breastfeeding mothers should consult a physician before use. Do not exceed one softgel daily without guidance; higher doses do not produce proportionally greater benefit and increase side effect risk.

Affron clinical trials measuring mood and emotional wellbeing outcomes typically show statistically significant improvements at 6–8 weeks of daily 30mg dosing. Some users report subtle mood improvements as early as 2–3 weeks. The mechanism involves modulation of serotonin, dopamine, and norepinephrine pathways, which require time to produce measurable behavioral effects.