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Sunergetic Annatto Tocotrienols 300mg — view 1 of 5
Sunergetic

Sunergetic Premium Annatto Tocotrienol Supplement - with DeltaGold - Tocotrienols Vitamin E 300 mg - Supports Liver, Immune & Heart Health - Delta + Gamma Tocotrienols (30 Liquid Capsules)

4.5· 393 Amazon reviews
$34.95$31.45with Subscribe & Save

$1.17/serving

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Price verified Apr 22, 2026

Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use

Our verdict

300mg tocotrienols per liquid capsule; 30 servings per bottle of DeltaGold Annatto Tocotrienols (Delta + Gamma) 300mg per liquid capsule (softgel) from Sunergetic. Best for users seeking a soy-free, annatto-derived…

Third-Party TestedSoy-freeDairy-freeGluten-freeNon-GMO

Why we recommend this

DeltaGold is one of the most research-backed tocotrienol ingredients — annatto-derived to avoid tocopherol interference, with human trials on NAFLD and cardiovascular markers. 300mg in a soy-free liquid capsule is competitive specialty positioning.

Check for interactions

Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.

Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.

What to watch out for

This specialty antioxidant has a narrower consumer audience than mainstream Vitamin E — dose-response relationships for tocotrienols vary by outcome. Without public COAs, buyers cannot verify full 300mg DeltaGold content.

Dose & form

Serving
300mg tocotrienols per liquid capsule; 30 servings per bottle
Form
Liquid Capsule (Softgel)
Clinical range
125-600mg/day tocotrienols in human trials for cardiovascular and liver endpoints
Dose adequacy
Full
Supply
30 servings · $1.17/serving
UPC
852207008385

Who it's best for

Users seeking a soy-free, annatto-derived tocotrienol supplement with branded DeltaGold ingredient for liver, immune, and heart health at clinically studied doses

Who should skip it

Shoppers who want mixed tocopherol Vitamin E or USP-verified tocotrienol certification

Pros

  • DeltaGold is a research-validated annatto-derived tocotrienol ingredient with published human trials
  • 300mg dose sits in the middle of the 125-600mg clinical tocotrienol research range
  • 100% tocotrienols with no tocopherols preserves tocotrienol bioavailability per Qureshi research
  • Soy-free, dairy-free, gluten-free, non-GMO profile suits most allergen needs

Cons

  • Third-party testing not publicly disclosed — no published COAs on the brand site
  • 393 reviews is a moderate (not flagship) track record for this SKU
  • Liquid capsule format may be harder to take for softgel-sensitive users

What customers say

4.5★ across 393 Amazon reviews. The most common questions from shoppers: re any potential interactions with medications, re any side effects from long-term use, and cause any digestive issues or side effects. Full answers in the FAQ below.

Frequently Asked Questions

What is the clinical dose for DeltaGold Annatto Tocotrienols (Delta + Gamma) 300mg?

Clinical trials typically use 125-600mg/day tocotrienols in human trials for cardiovascular and liver endpoints. Sunergetic Annatto Tocotrienols 300mg delivers 300mg tocotrienols per liquid capsule; 30 servings per bottle, which we classify as Full relative to that range.

How does Sunergetic Annatto Tocotrienols 300mg compare to similar Liquid Capsule (Softgel)?

See the "Also consider" section below for two alternatives. Choose based on form preference (Liquid Capsule (Softgel) vs alternatives), dose adequacy, and third-party testing.

Is Sunergetic Annatto Tocotrienols 300mg third-party tested?

Yes — GMP manufactured; third-party testing not publicly disclosed. Third-party testing verifies ingredient identity and label accuracy.

Does this work with Amazon Subscribe & Save?

Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.

Are there any potential interactions with medications?

Tocotrienols may enhance blood thinners (warfarin, aspirin) due to mild anticoagulant activity — consult your doctor if on anticoagulation therapy. Tocotrienols can also affect statin metabolism and may slightly reduce cholesterol-lowering statin effects. No major interactions with blood pressure or diabetes medications are documented at 300mg daily.

Are there any side effects from long-term use?

Tocotrienol use up to 24 weeks has been studied in human trials with excellent safety. DeltaGold has been evaluated at doses up to 900mg/day without serious adverse events. Long-term safety beyond 12 months lacks large-scale data but extensive post-market use suggests good tolerability at 300mg daily.

Does it cause any digestive issues or side effects?

Tocotrienols in liquid capsule form are typically well tolerated because the oil-based delivery matches dietary fat absorption. Rare reports of mild nausea or fat-related GI discomfort occur when taken without food. Taking with a fatty meal resolves most tolerability issues. The softgel format is gentle on the stomach.

Can it be taken with other supplements or vitamins?

Tocotrienols pair well with CoQ10, omega-3 fatty acids, and Vitamin K2 for cardiovascular stacks. Avoid combining with high-dose alpha-tocopherol (standard Vitamin E) — alpha-tocopherol interferes with tocotrienol absorption. Quality tocotrienol brands recommend separating tocopherol and tocotrienol intake by several hours.

Are there any specific instructions for taking it safely?

Take 1 liquid capsule daily with a meal containing fat to maximize absorption. Tocotrienols are fat-soluble — fasted dosing reduces bioavailability. Store tightly capped to prevent oil oxidation. Avoid taking with standard Vitamin E (alpha-tocopherol). Consult your physician if you take anticoagulants.

How long until benefits are typically experienced?

Hepatic and antioxidant benefits typically emerge within 4-12 weeks of daily use in clinical trials. The NAFLD study by Magosso et al. (2013) showed improvements in fatty liver markers at 12 weeks at 200-400mg. Cardiovascular markers like hs-CRP have changed at 8-24 weeks. Consistency matters more than dose timing.

Also consider

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This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer