Premium Kidney Cleanse Supplement - Powerful Kidney Support Formula With Cranberry and Astragalus - Helps Support Healthy Kidneys & Urinary Tract Support - Kidney Cleanse Detox & Repair - 60 Capsules
$0.28/serving
Price verified Apr 22, 2026
Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use
Our verdict
2 capsules daily; 30 servings per bottle; multi-botanical blend of Cranberry + Astragalus + Nettle per capsule from Sunergetic. Best for users seeking a flagship multi-ingredient kidney and urinary tract…
Why we recommend this
One of the most-reviewed kidney support products on Amazon with 10,697 ratings at 4.5 stars signals exceptional consumer satisfaction and consistency. The cranberry + astragalus + nettle combination targets multiple urinary and kidney support pathways.
Check for interactions
Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.
Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.
What to watch out for
Without per-ingredient dose disclosure, users cannot verify each component matches published clinical ranges. Kidney disease is a medical condition requiring physician management — this product is complementary support, not therapy.
Dose & form
- Serving
- 2 capsules daily; 30 servings per bottle; multi-botanical blend
- Form
- Capsule
- Clinical range
- Cranberry: 500mg/day for UTI prevention; Astragalus: 500-2000mg/day; Nettle: 300-600mg/day
- Dose adequacy
- Blend
- Supply
- 60 servings · $0.28/serving
- UPC
- 852207008613
Who it's best for
Users seeking a flagship multi-ingredient kidney and urinary tract support blend with cranberry, astragalus, and nettle, backed by 10,000+ consumer reviews
Who should skip it
Users with active kidney disease requiring medical management or those seeking concentrated D-mannose for UTI prevention
Pros
- Flagship 10,697 reviews at 4.5 stars — one of the most-reviewed kidney support products on Amazon
- Three-ingredient synergy: cranberry (UTI), astragalus (kidney function), nettle (diuretic support)
- Multi-pathway support for kidney filtration, urinary tract, and overall urinary health
- Value pricing at $16.95 for a 30-day supply of multi-botanical formula
Cons
- Third-party testing not publicly disclosed — no published COAs on the brand site
- Individual ingredient doses not disclosed on product bullets
- Not a substitute for medical management of kidney disease
What customers say
4.5★ across 10,697 Amazon reviews. The most common questions from shoppers: re any potential interactions with medications, re any side effects from long-term use, and cause any digestive issues or side effects. Full answers in the FAQ below.
Frequently Asked Questions
What is the clinical dose for Cranberry + Astragalus + Nettle?
What is the clinical dose for Cranberry + Astragalus + Nettle?
Clinical trials typically use Cranberry: 500mg/day for UTI prevention; Astragalus: 500-2000mg/day; Nettle: 300-600mg/day. Sunergetic Kidney Cleanse Cranberry delivers 2 capsules daily; 30 servings per bottle; multi-botanical blend, which we classify as Blend relative to that range.
How does Sunergetic Kidney Cleanse Cranberry compare to similar Capsule?
How does Sunergetic Kidney Cleanse Cranberry compare to similar Capsule?
See the "Also consider" section below for two alternatives. Choose based on form preference (Capsule vs alternatives), dose adequacy, and third-party testing.
Is Sunergetic Kidney Cleanse Cranberry third-party tested?
Is Sunergetic Kidney Cleanse Cranberry third-party tested?
Yes — GMP manufactured; third-party testing not publicly disclosed. Third-party testing verifies ingredient identity and label accuracy.
Does this work with Amazon Subscribe & Save?
Does this work with Amazon Subscribe & Save?
Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.
Are there any potential interactions with medications?
Are there any potential interactions with medications?
Astragalus can affect immune function and may interact with immunosuppressants (cyclosporine, tacrolimus). Nettle has mild diuretic and blood pressure lowering effects — monitor if on antihypertensive medications or lithium. Cranberry may enhance warfarin effects — consult your doctor if on anticoagulation. Inform your physician if you have any kidney disease before starting.
Are there any side effects from long-term use?
Are there any side effects from long-term use?
Cranberry, astragalus, and nettle have centuries of traditional use and favorable human trial safety profiles. Long-term daily use is generally well tolerated. Astragalus has been studied for 6+ months in clinical trials. Annual kidney function blood tests (BUN, creatinine, eGFR) are reasonable with chronic urinary supplementation.
Does it cause any digestive issues or side effects?
Does it cause any digestive issues or side effects?
Generally well tolerated. Cranberry extract can occasionally cause mild stomach upset — taking with food helps. Nettle is gentle on digestion. Astragalus may cause mild stomach cramps at higher doses. Stay well hydrated to support kidney filtration and minimize any tract irritation.
Can it be taken with other supplements or vitamins?
Can it be taken with other supplements or vitamins?
Pairs well with magnesium, Vitamin C (supports urinary acidification), and D-mannose for enhanced UTI prevention. Avoid stacking with other diuretic supplements to prevent electrolyte imbalance. Do not combine with prescription diuretics without physician oversight.
Are there any specific instructions for taking it safely?
Are there any specific instructions for taking it safely?
Take 2 capsules daily with water and a meal. Drink plenty of additional water throughout the day — adequate hydration is the foundation of kidney and urinary health. Monitor for any urinary tract symptoms (burning, urgency) and consult a doctor if they occur. Do not use as substitute for prescribed kidney therapy.
How long until benefits are typically experienced?
How long until benefits are typically experienced?
UTI prevention effects from cranberry typically emerge after 2-4 weeks of daily use. Kidney function support is cumulative over 2-3 months. Diuretic effects from nettle may be felt within days. Overall urinary health benefits build over 4-12 weeks with consistent daily supplementation.
