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Sunergetic Magnesium Oxide Citrate 500mg — view 1 of 5
Sunergetic

Premium Magnesium Citrate Capsules - Powerful 500mg Magnesium Oxide & Citrate Supplement - Helps Support Healthy Bones, Muscles, Teeth, Energy & Relaxation - 120 Vegetable Capsules

4.6· 4,222 Amazon reviews
$16.95$16.10with Subscribe & Save

$0.14/serving

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Price verified Apr 22, 2026

Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use

Our verdict

500mg magnesium per 2-capsule serving; 60 servings per bottle of Magnesium Oxide + Magnesium Citrate 500mg per capsule (vegetable) from Sunergetic. Best for users seeking a high-dose magnesium oxide/citrate capsule…

Third-Party TestedCapsule (Vegetable)Subscribe & SaveClinical Dose

Why we recommend this

One of the highest-rated magnesium supplements on Amazon with 4,222 reviews at 4.6 stars. The oxide + citrate combination provides both broad mineral supply (oxide) and better-absorbed citrate component. At $16.95 for 60 servings, value per dose is exceptional.

Check for interactions

Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.

Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.

What to watch out for

The magnesium oxide form has notably lower bioavailability than glycinate or citrate alone — some research suggests as low as 4% absorption for oxide. Users with sensitive digestion may experience loose stools from oxide at this dose. For targeted neurological benefits (cognition, sleep), glycinate or threonate forms are better options.

Dose & form

Serving
500mg magnesium per 2-capsule serving; 60 servings per bottle
Form
Capsule (Vegetable)
Clinical range
200-400mg elemental magnesium daily
Dose adequacy
Full
Supply
120 servings · $0.14/serving
UPC
852207008620

Who it's best for

Users seeking a high-dose magnesium oxide/citrate capsule for bone, muscle, energy, and relaxation support at a value price point

Who should skip it

Users needing highly bioavailable forms like magnesium glycinate or threonate for specific neurological support

Pros

  • 500mg meets adult RDA and matches clinical dose ranges for sleep and muscle support
  • Vegetable capsule is suitable for vegetarian and vegan users
  • Flagship 4,222 reviews at 4.6 stars indicates strong consumer satisfaction
  • 120-capsule bottle at $16.95 provides excellent value per serving

Cons

  • Third-party testing not publicly disclosed — no published COAs on the brand site
  • Magnesium oxide has lower bioavailability than glycinate or threonate
  • May exceed supplemental UL of 350mg for sensitive users

What customers say

4.6★ across 4,222 Amazon reviews. The most common questions from shoppers: re any potential interactions with medications, re any side effects from long-term use, and cause any digestive issues or side effects. Full answers in the FAQ below.

Frequently Asked Questions

What is the clinical dose for Magnesium Oxide + Magnesium Citrate 500mg?

Clinical trials typically use 200-400mg elemental magnesium daily. Sunergetic Magnesium Oxide Citrate 500mg delivers 500mg magnesium per 2-capsule serving; 60 servings per bottle, which we classify as Full relative to that range.

How does Sunergetic Magnesium Oxide Citrate 500mg compare to similar Capsule (Vegetable)?

See the "Also consider" section below for two alternatives. Choose based on form preference (Capsule (Vegetable) vs alternatives), dose adequacy, and third-party testing.

Is Sunergetic Magnesium Oxide Citrate 500mg third-party tested?

Yes — GMP manufactured; third-party testing not publicly disclosed. Third-party testing verifies ingredient identity and label accuracy.

Does this work with Amazon Subscribe & Save?

Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.

Are there any potential interactions with medications?

Magnesium can interact with antibiotics (tetracyclines, quinolones) — separate by 2-4 hours. Magnesium may enhance the muscle-relaxant effect of calcium channel blockers. Bisphosphonates (osteoporosis medications) should be separated from magnesium. Generally safe with most other medications at this dose.

Are there any side effects from long-term use?

Magnesium at 500mg daily has favorable long-term safety in adults with normal kidney function. Users with chronic kidney disease should avoid high-dose magnesium supplementation without physician oversight due to reduced excretion capacity. No known long-term toxicity in healthy adults.

Does it cause any digestive issues or side effects?

Magnesium oxide is known to cause loose stools or diarrhea in some users — this is why it's commonly used as a laxative. Taking with food reduces GI effects. Citrate form has milder GI effects. Start with 1 capsule daily to assess tolerance before moving to 2 capsules.

Can it be taken with other supplements or vitamins?

Pairs well with calcium (2:1 calcium:magnesium ratio), Vitamin D, Vitamin K2, and zinc for bone health stacks. Also pairs with B-complex for energy support. Avoid stacking with other magnesium products to prevent exceeding 500-600mg daily total.

Are there any specific instructions for taking it safely?

Take 2 capsules daily with food to minimize GI effects and improve absorption. Evening dosing supports relaxation and sleep benefits. Separate from antibiotics and bisphosphonates by 2-4 hours. Stay well hydrated. Consult physician if you have kidney disease.

How long until benefits are typically experienced?

Sleep and muscle relaxation benefits often emerge within 1-2 weeks of daily supplementation. Magnesium deficiency correction in cellular stores takes 4-12 weeks. Bone health benefits are cumulative over months. Benefits depend heavily on baseline magnesium status.

Also consider

Part of this guide

Best Magnesium Supplements

As an Amazon Associate, we earn from qualifying purchases. Some links below are affiliate links — this doesn't affect our editorial independence or product ratings. How we evaluate products

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer