Doctor's Best High Absorption Magnesium Glycinate Lysinate Supplement for Sleep Support - Chelated Magnesium Tablets for Women & Men, 200mg per Serving, Supports Calm & Relaxation, Vegan - 240 Count
$0.17/serving
Price verified Apr 22, 2026
Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use
Our verdict
200mg elemental Mg per serving of Magnesium Glycinate/Lysinate Chelate per tablet from Doctor's BEST. Best for overall / Sleep support.
Why we recommend this
Chelated magnesium glycinate with high bioavailability at an excellent price point. Glycinate absorbs 4-5x better than oxide, and this product delivers a full clinical dose at $0.14/serving. Over 74,000 Amazon reviews with a 4.5-star average.
Check for interactions
Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.
Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.
What to watch out for
Requires 2 tablets per serving; tablets are relatively large.
Dose & form
- Serving
- 200mg elemental Mg per serving
- Form
- Tablet
- Clinical range
- 200-400mg elemental magnesium daily
- Dose adequacy
- Therapeutic
- Supply
- 120 servings · $0.17/serving
- UPC
- 753950000872
Who it's best for
Overall / Sleep support
Who should skip it
Those who struggle swallowing large tablets
Pros
- High bioavailability (glycinate chelate)
- Full clinical dose (200mg elemental)
- Excellent value at $0.14/serving
- Over 74,000 reviews, 4.5-star average
Cons
- Requires 2 tablets per serving
- Tablets are relatively large
What customers say
4.6★ across 75,132 Amazon reviews. The most common questions from shoppers: re any potential interactions with medications, re any side effects from long-term use, and cause any digestive issues or side effects. Full answers in the FAQ below.
Frequently Asked Questions
What is the clinical dose for Magnesium Glycinate/Lysinate Chelate?
What is the clinical dose for Magnesium Glycinate/Lysinate Chelate?
Clinical trials typically use 200-400mg elemental magnesium daily. Doctor's Best High Absorption Magnesium Glycinate delivers 200mg elemental Mg per serving, which we classify as Therapeutic relative to that range.
How does Doctor's Best High Absorption Magnesium Glycinate compare to similar Tablet?
How does Doctor's Best High Absorption Magnesium Glycinate compare to similar Tablet?
See the "Also consider" section below for two alternatives. Choose based on form preference (Tablet vs alternatives), dose adequacy, and third-party testing.
Is Doctor's Best High Absorption Magnesium Glycinate third-party tested?
Is Doctor's Best High Absorption Magnesium Glycinate third-party tested?
Yes — Third-Party Tested. Third-party testing verifies ingredient identity and label accuracy.
Does this work with Amazon Subscribe & Save?
Does this work with Amazon Subscribe & Save?
Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.
Are there any potential interactions with medications?
Are there any potential interactions with medications?
Magnesium glycinate may interact with antibiotics (tetracyclines, fluoroquinolones) — space doses 2+ hours apart. It can also reduce absorption of bisphosphonates and blood pressure medications. Doctor's Best does not contain additional herbs or stimulants that would cause further interactions.
Are there any side effects from long-term use?
Are there any side effects from long-term use?
At 200mg elemental magnesium per serving, Doctor's Best is within the tolerable upper intake level (350mg from supplements). Long-term use at this dose is generally well-tolerated. Glycinate is one of the gentlest forms on the GI tract, making it suitable for daily use.
Does it cause any digestive issues or side effects?
Does it cause any digestive issues or side effects?
Magnesium glycinate is one of the least likely forms to cause digestive issues. Unlike citrate or oxide, glycinate does not have a significant laxative effect. The chelated form is gentle on the stomach and can be taken any time of day.
Can it be taken with other supplements or vitamins?
Can it be taken with other supplements or vitamins?
Yes. Magnesium glycinate pairs well with vitamin D (enhances magnesium absorption), zinc (take at different times to avoid competition), and B vitamins. Avoid taking simultaneously with calcium supplements, as they compete for absorption.
Are there any specific instructions for taking it safely?
Are there any specific instructions for taking it safely?
Take 2 tablets daily with or without food. Doctor's Best recommends splitting the dose (1 tablet morning, 1 evening) for optimal absorption. Those with kidney disease should consult a physician before supplementing magnesium.
How long until benefits are typically experienced?
How long until benefits are typically experienced?
Most users report improved sleep quality within 1-2 weeks of consistent use. Muscle relaxation benefits may be noticed within days. Full magnesium repletion for deficient individuals typically takes 4-6 weeks of daily supplementation.
Also consider
Double Wood Magnesium Malate 1500mg
Capsule · Magnesium Malate (magnesium bonded to malic acid) · $14.95
$14.95
Sports Research Magnesium L-Threonate 2000mg with Magtein (180 Capsules)
Capsule · Magnesium L-Threonate (as Magtein, patented MIT ingredient) — 2000mg per 4-capsule serving (144mg elemental magnesium) · $58.95
$58.95
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