THORNE - Hormone Advantage - Estrogen Support & Hormone Balance for Men & Women* - Featuring DIM & Pomegranate Extract - Gluten, Dairy & Soy-Free - 60 Servings

Clinical trials typically use 100-200mg bioavailable DIM daily. Thorne DIM Advantage delivers 100mg BioResponse DIM per capsule, which we classify as Therapeutic relative to that range.

See the "Also consider" section below for two alternatives. Choose based on form preference (Capsule vs alternatives), dose adequacy, and third-party testing.

Yes — NSF Certified for Sport. Third-party testing verifies ingredient identity and label accuracy.

Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.

Thorne DIM Advantage is considered safe for daily use. Thorne is NSF Certified for Sport, one of the highest quality certifications in the supplement industry. The product is trusted by Mayo Clinic and US Olympic teams. Consult your healthcare provider before starting, especially if you take hormonal medications.

NSF Certified for Sport is a rigorous third-party certification that tests for over 270 banned substances, verifies label accuracy, and confirms GMP manufacturing. It is required by many professional sports organizations. This certification gives Thorne DIM Advantage one of the highest quality assurance levels in the supplement industry.

DIM affects estrogen metabolism and could potentially interact with hormone therapies, hormonal contraceptives, and certain cancer treatments. Thorne recommends consulting your healthcare provider before use if you take any prescription medications. Their practitioner-grade quality means many doctors are familiar with this product.

Many menopausal women use DIM for estrogen metabolism support. The BioResponse DIM in Thorne DIM Advantage is well-absorbed, so the 100mg dose delivers meaningful bioavailable DIM. Consult your healthcare provider, especially if you are on hormone replacement therapy.

BioResponse DIM absorbs 50-100x better than crystalline DIM, so even the 100mg dose delivers significant bioavailable DIM. Temporary changes in urine color are common and harmless. Some users report mild headaches initially. Because of the enhanced absorption, there's no need for the higher 200mg dose used in less bioavailable products.

The recommended dose is one capsule daily with a meal. Each capsule provides 100mg of BioResponse DIM. For a higher dose, some practitioners recommend two capsules daily (200mg), but this should be discussed with your healthcare provider.