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Vitamin C 500 mg, vitamin E 400 IU, zinc 80 mg, copper 2 mg, lutein 10 mg, zeaxanthin 2 mg — typically 2 capsules daily
Maximum dose: Follow the standard AREDS2 dosage; zinc at 80 mg is already near the upper tolerable limit (40 mg UL, though 80 mg was well-tolerated in the trial)
General recommendation: Vitamin C 500 mg, vitamin E 400 IU, zinc 80 mg, copper 2 mg, lutein 10 mg, zeaxanthin 2 mg — typically 2 capsules daily
Timing: Divided into two doses daily (morning and evening) with meals • Take with food for best absorption.
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Intermediate AMD (both eyes) | Full AREDS2 formula daily | Strong |
| Advanced AMD in one eye | Full AREDS2 formula daily | Strong |
| Early AMD / prevention | Not proven beneficial — AREDS2 studied intermediate-to-advanced AMD | Moderate |
Upper limit: Follow the standard AREDS2 dosage; zinc at 80 mg is already near the upper tolerable limit (40 mg UL, though 80 mg was well-tolerated in the trial)
Divided into two doses daily (morning and evening) with meals
Best taken with food for optimal absorption.