Bilberry Research & Evidence

SupplementScience.ai Editorial Team·Evidence-Based Supplement Research

Published Mar 11, 2026

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Evidence Level

Moderate

Bilberry has a moderate evidence base for eye health. A 2012 systematic review identified 30 clinical trials, noting that while earlier studies were methodologically weak, newer RCTs show benefits for eye fatigue and retinal microcirculation. The anthocyanin content is the primary active component, and standardized extracts (25-36% anthocyanins) are recommended for consistent effects.

Evidence by Condition

Condition	Studied Dose	Evidence
Eye fatigue / screen strain	480 mg standardized extract daily	Moderate
General eye health	160-320 mg daily	Moderate
Retinal support	320-480 mg daily	Emerging

Full Bilberry Guide

References

Ozawa Y, Kawashima M, Inoue S, et al. (2015). Bilberry extract supplementation for preventing eye fatigue in video display terminal workers. Journal of Nutrition, Health and Aging. DOI PubMed
Canter PH, Ernst E (2004). Anthocyanosides of Vaccinium myrtillus (bilberry) for night vision — a systematic review of placebo-controlled trials. Survey of Ophthalmology. DOI PubMed
Kalt W, Cassidy A, Howard LR, et al. (2020). Recent Research on the Health Benefits of Blueberries and Their Anthocyanins. Advances in Nutrition. DOI PubMed