Evidence Level
Bilberry is a well-researched supplement with notable effects on eye health and cardiometabolic markers. A 2015 study by Ozawa et al. demonstrated that bilberry extract supplementation can help alleviate eye fatigue in video display terminal workers, highlighting its potential benefits for digital screen users. The anthocyanin content, particularly the standardized extracts containing 25-36% anthocyanins, is crucial for consistent effects (Ozawa et al., 2015).
In terms of cardiometabolic health, a systematic review and meta-analysis by Talebi et al. (2025) involving 11 RCTs (n=409) found that bilberry supplementation may modestly improve HbA1c and triglycerides but does not significantly affect other cardiometabolic markers. Additionally, a systematic review by Grohmann et al. (2021) of 24 studies reported that bilberry extracts can reduce HbA1c and cholesterol in certain populations, further supporting its role in metabolic health.
Regarding eye health, Canter and Ernst (2004) conducted a systematic review of 12 placebo-controlled trials, concluding that while there is no strong evidence to support the use of bilberry anthocyanosides for improving night vision in healthy individuals, some weaker studies suggest potential benefits. This highlights the need for further research to confirm these findings.
Overall, bilberry appears to have moderate evidence supporting its use for eye health and cardiometabolic benefits, with standardized extracts being key for consistent outcomes.