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Types of Vitamin B7 (Biotin): Forms & Bioavailability

Evidence:Moderate
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This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

Forms Comparison

FormBioavailabilityBest For
D-BiotinHighGeneral supplementation — the only biologically active form of biotin
Biotin bound to lysine (Biocytin)ModerateFood-derived form — found naturally in foods, requires biotinidase for release

D-Biotin

Bioavailability: High. Best for: General supplementation — the only biologically active form of biotin.

Biotin bound to lysine (Biocytin)

Bioavailability: Moderate. Best for: Food-derived form — found naturally in foods, requires biotinidase for release.

References

  1. ReviewPatel DP, Swink SM, Castelo-Soccio L (2017). A review of the use of biotin for hair loss. Skin Appendage Disorders. DOI PubMed
  2. FDA Safety Communication (2017). The FDA warns that biotin may interfere with lab tests. U.S. Food and Drug Administration.
  3. ObservationalColombo VE, Gerber F, Bronhofer M, Floersheim GL (1990). Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy. Journal of the American Academy of Dermatology. DOI PubMed