CBD — Frequently Asked Questions
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Frequently Asked Questions
Will CBD make me feel high?
Will CBD make me feel high?
No — CBD is non-psychoactive and does not produce the intoxication or euphoria associated with THC. Full-spectrum CBD products contain trace amounts of THC (less than 0.3% by law), but this is far too little to cause psychoactive effects. If you are concerned about any THC exposure (e.g., for drug testing), choose broad-spectrum or isolate products.
How do I choose a quality CBD product?
How do I choose a quality CBD product?
The CBD market has significant quality issues — studies have found many products contain less CBD than labeled, or contain unlisted THC. Look for: (1) third-party certificate of analysis (COA) from an independent lab, (2) NSF, USP, or ISO 17025-accredited testing, (3) clear labeling of CBD content per serving (not just hemp extract), and (4) extraction method (CO2 extraction is preferred). Avoid products that make therapeutic claims or lack transparency about testing.
Can CBD interact with my medications?
Can CBD interact with my medications?
Yes — this is a significant concern. CBD inhibits CYP3A4 and CYP2C19 liver enzymes, which metabolize approximately 60% of all pharmaceuticals. This can increase blood levels of statins, blood thinners, calcium channel blockers, benzodiazepines, and many other drugs. A practical rule: if your medication has a grapefruit warning, CBD may interact with it similarly. Always consult your pharmacist or physician before starting CBD if you take any regular medications.
References
- Shannon S, Lewis N, Lee H, Hughes S (2019). Cannabidiol in anxiety and sleep: a large case series. Permanente Journal. DOI PubMed
- Linares IM, Zuardi AW, Pereira LC, et al. (2019). Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test. Brazilian Journal of Psychiatry. DOI PubMed
- Zuardi AW, Cosme RA, Graeff FG, Guimarães FS (1993). Effects of ipsapirone and cannabidiol on human experimental anxiety. Journal of Psychopharmacology. DOI PubMed
- Blessing EM, Steenkamp MM, Manzanares J, Marmar CR (2015). Cannabidiol as a potential treatment for anxiety disorders. Neurotherapeutics. DOI PubMed