General Dosage
350 mg daily (wheat-derived) or 40 mg daily (rice-derived)
Maximum dose: 350 mg/day for wheat-derived is the standard clinical dose; higher doses not studied
Ceramides (Phytoceramides) Dosage Guide
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 350 mg daily (wheat-derived) or 40 mg daily (rice-derived)
Timing: Take with a meal for optimal absorption of these lipid-based compounds • Take with food for best absorption.
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Dry skin and hydration | 350 mg daily for 4-12 weeks | Moderate |
| Skin barrier repair | 350 mg daily | Moderate |
| Skin roughness | 40 mg daily (rice-derived) for 6 weeks | Moderate |
Upper limit: 350 mg/day for wheat-derived is the standard clinical dose; higher doses not studied
Timing & Absorption
Take with a meal for optimal absorption of these lipid-based compounds
Best taken with food for optimal absorption.
References
- Guillou S, Ghabri S, Jeantet C, et al. (2011). The moisturizing effect of a wheat extract food supplement on women's skin: a randomized, double-blind placebo-controlled trial. International Journal of Cosmetic Science. DOI PubMed
- Asai S, Miyachi H. (2003). Evaluation of skin moisturizing effect of oral intake of glucosylceramides derived from rice. Journal of Oleo Science.
- Imokawa G. (2009). A possible mechanism underlying the ceramide deficiency in atopic dermatitis. Journal of Dermatological Science. DOI PubMed
- Tessema EN, Gebre-Mariam T, Neubert RHH, Wohlrab J. (2017). Potential applications of phyto-derived ceramides in improving epidermal barrier function. Skin Pharmacology and Physiology. DOI PubMed