General Dosage
0.9-2mg daily
Maximum dose: 10mg/day (NIH UL); liver toxicity possible above this
Copper Dosage Guide
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 0.9-2mg daily
Timing: With food to reduce nausea; separate from zinc supplements by 2 hours if taking both individually • Take with food for best absorption.
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Zinc-induced copper depletion prevention | 1-2mg daily when taking >30mg zinc | Strong |
| General health | 0.9mg daily (RDA) | Moderate |
| Connective tissue support | 1-2mg daily | Emerging |
Upper limit: 10mg/day (NIH UL); liver toxicity possible above this
Timing & Absorption
With food to reduce nausea; separate from zinc supplements by 2 hours if taking both individually
Best taken with food for optimal absorption.
References
- Willis MS, Monaghan SA, Miller ML, et al. (2005). Zinc-induced copper deficiency: a report of three cases initially recognized on bone marrow examination. American Journal of Clinical Pathology. DOI PubMed
- Turnlund JR, Jacob RA, Keen CL, et al. (2004). Long-term high copper intake: effects on indexes of copper status, antioxidant status, and immune function in young men. American Journal of Clinical Nutrition. DOI PubMed
- Bost M, Houdart S, Oberli M, Kalonji E, Huneau JF, Margaritis I (2016). Dietary copper and human health: Current evidence and unresolved issues. Journal of Trace Elements in Medicine and Biology. DOI PubMed