General Dosage
2g D-mannose daily dissolved in water for UTI prevention
Maximum dose: 8-10g daily during acute episodes has been used anecdotally; 2g daily is the standard preventive dose
D-Mannose Dosage Guide
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Dosage Recommendations
General recommendation: 2g D-mannose daily dissolved in water for UTI prevention
Timing: Before bed (after last urination) or upon waking; ensure bladder is empty before dosing to maximize bladder concentration
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Recurrent UTI prevention | 2g once daily | Moderate |
| Post-intercourse UTI prevention | 2g within 2 hours after intercourse | Emerging |
| Acute UTI support (adjunct) | 1.5g every 2-3 hours for 3 days, then 2g daily | Emerging |
Upper limit: 8-10g daily during acute episodes has been used anecdotally; 2g daily is the standard preventive dose
Timing & Absorption
Before bed (after last urination) or upon waking; ensure bladder is empty before dosing to maximize bladder concentration
Can be taken with or without food.
References
- Kranjčec B, Papeš D, Altarac S (2014). D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial. World Journal of Urology. DOI PubMed
- Porru D, Parmigiani A, Tinelli C, et al. (2014). Oral D-mannose in recurrent urinary tract infections in women: a pilot study. Journal of Clinical Urology. DOI