Fadogia Agrestis — Frequently Asked Questions
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Frequently Asked Questions
Is fadogia agrestis safe to take?
Is fadogia agrestis safe to take?
The honest answer is that we do not know. No human clinical trials have been published. The only data comes from rat studies, which showed testicular toxicity at higher doses (100 mg/kg). While lower doses showed testosterone increases without apparent toxicity in rats, animal results do not always translate to humans. If you choose to use fadogia agrestis, do so under medical supervision with regular blood work monitoring liver function, kidney function, and hormone panels.
What dose of fadogia agrestis should I take?
What dose of fadogia agrestis should I take?
There is no established human dosage based on clinical trials. The commonly recommended dose of 300-600mg daily is extrapolated from animal data and supplement industry convention, not from human research. The rat studies used 18-100 mg/kg body weight, with toxicity at the highest dose. Until human pharmacokinetic and safety studies are published, any dosing recommendation carries significant uncertainty.
Should I stack fadogia agrestis with tongkat ali?
Should I stack fadogia agrestis with tongkat ali?
This combination was popularized by podcast discussions but has never been studied in any clinical trial — neither individually in humans (for fadogia) nor in combination. Tongkat ali has moderate human evidence, while fadogia has none. Stacking two supplements that affect testosterone through different mechanisms introduces unknown interaction risks. If you choose to combine them, do so under medical supervision with baseline and follow-up hormone panels.
References
- Yakubu MT, Akanji MA, Oladiji AT (2005). Aphrodisiac potentials of the aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem in male albino rats. Asian Journal of Andrology. DOI PubMed
- Yakubu MT, Akanji MA, Oladiji AT, Adesokan AA (2008). Androgenic potentials of aqueous extract of Fadogia agrestis stem in male Wistar rats. Asian Journal of Andrology. DOI PubMed