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Types of Hawthorn Berry: Forms & Bioavailability

Evidence:Moderate
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This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

Forms Comparison

FormBioavailabilityBest For
WS 1442 (Standardized Extract)HighMost studied — standardized to 18.75% OPCs; used in nearly all major clinical trials
LI 132 (Standardized Extract)HighAlternative clinical-grade extract — standardized to 2.2% flavonoids, well-studied in heart failure
Berry/Leaf Powder CapsulesLow-ModerateTraditional use — whole plant material, less potent than standardized extracts

WS 1442 (Standardized Extract)

Bioavailability: High. Best for: Most studied — standardized to 18.75% OPCs; used in nearly all major clinical trials.

LI 132 (Standardized Extract)

Bioavailability: High. Best for: Alternative clinical-grade extract — standardized to 2.2% flavonoids, well-studied in heart failure.

Berry/Leaf Powder Capsules

Bioavailability: Low-Moderate. Best for: Traditional use — whole plant material, less potent than standardized extracts.

References

  1. Meta-analysisPittler MH, Guo R, Ernst E (2008). Hawthorn extract for treating chronic heart failure. Cochrane Database of Systematic Reviews. DOI PubMed
  2. RCTHolubarsch CJ, Colucci WS, Meinertz T, Gaus W, Tendera M (2008). The efficacy and safety of Crataegus extract WS 1442 in patients with heart failure: the SPICE trial. European Journal of Heart Failure. DOI PubMed
  3. RCTWalker AF, Marakis G, Simpson E, Hope JL, Robinson PA, Hassanein M, Simpson HC (2006). Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trial. British Journal of General Practice. PubMed
  4. RCTZand J, Lanza F, Garg HK, Bryan NS (2011). All-natural nitrite and nitrate containing dietary supplement promotes nitric oxide production and reduces triglycerides in humans.. Nutrition research (New York, N.Y.). DOI PubMed