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Holy Basil (Tulsi) Side Effects & Safety

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

Safety Profile

Overall safety rating: Generally Safe

Potential Side Effects

  • Generally well-tolerated at recommended doses
  • Mild nausea in some individuals
  • May lower blood sugar — monitor if diabetic
  • May have mild anti-fertility effects (high-dose animal studies)

Drug & Supplement Interactions

  • May enhance effects of blood sugar-lowering medications
  • May have additive effects with anticoagulant/antiplatelet drugs (eugenol inhibits platelet aggregation)
  • May slow blood clotting — discontinue 2 weeks before surgery
  • Avoid during pregnancy due to potential uterotonic effects

Maximum Dose

Do not exceed: 1200mg extract daily (higher doses not well-studied long-term)

References

  1. (). The Clinical Efficacy and Safety of Tulsi in Humans: A Systematic Review of the Literature. Evidence-Based Complementary and Alternative Medicine. DOI
  2. (). Efficacy of an Extract of Ocimum tenuiflorum (OciBest) in the Management of General Stress. Journal of Ayurveda and Integrative Medicine. DOI