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SupplementScience

Iron Dosage Guide

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

18-65mg elemental iron daily for deficiency correction; 8-18mg for maintenance

Maximum dose: 45mg/day elemental iron for adults (NIH UL); therapeutic doses up to 65mg under medical supervision

Dosage Recommendations

General recommendation: 18-65mg elemental iron daily for deficiency correction; 8-18mg for maintenance

Timing: On an empty stomach for best absorption; with vitamin C to enhance absorption; avoid with tea, coffee, dairy, or calcium within 2 hours

Dosage by Condition

ConditionRecommended DoseEvidence
Iron-deficiency anemia65mg elemental iron 1-2x dailyStrong
Non-anemic iron deficiency25-45mg elemental iron daily or every other dayStrong
Pregnancy27-60mg elemental iron daily per WHO guidelinesStrong
Athletic performance25-45mg daily for iron-depleted athletesModerate

Upper limit: 45mg/day elemental iron for adults (NIH UL); therapeutic doses up to 65mg under medical supervision

Timing & Absorption

On an empty stomach for best absorption; with vitamin C to enhance absorption; avoid with tea, coffee, dairy, or calcium within 2 hours

Can be taken with or without food.

References

  1. (). Effect of iron supplementation on fatigue in nonanemic menstruating women with low ferritin: a randomized controlled trial. CMAJ. DOI
  2. (). Iron absorption from oral iron supplements given on consecutive versus alternate days and as single morning doses versus twice-daily split doses. The Lancet Haematology. DOI
  3. (). Iron deficiency. The Lancet. DOI