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Magnolia Bark Dosage Guide

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

200-500mg standardized magnolia bark extract daily, or 250mg Relora 2-3 times daily

Maximum dose: 750mg/day Relora or 500mg/day concentrated magnolia extract (limited data above these levels)

Dosage Recommendations

General recommendation: 200-500mg standardized magnolia bark extract daily, or 250mg Relora 2-3 times daily

Timing: For stress: divided doses throughout the day. For sleep: single dose 30-60 minutes before bed.

Dosage by Condition

ConditionRecommended DoseEvidence
Stress and cortisol management250mg Relora, 3 times daily (750mg total)Emerging
Sleep support200-400mg magnolia bark extract before bedEmerging
Anxiety200-500mg standardized extract dailyEmerging

Upper limit: 750mg/day Relora or 500mg/day concentrated magnolia extract (limited data above these levels)

Timing & Absorption

For stress: divided doses throughout the day. For sleep: single dose 30-60 minutes before bed.

Can be taken with or without food.

Full Magnolia Bark Guide

References

  1. (). Effect of Magnolia officinalis and Phellodendron amurense (Relora) on cortisol and psychological mood state in moderately stressed subjects. Journal of the International Society of Sports Nutrition. DOI
  2. (). The natural products magnolol and honokiol are positive allosteric modulators of both synaptic and extra-synaptic GABA(A) receptors. Neuropharmacology. DOI
  3. (). Honokiol, a putative anxiolytic agent extracted from magnolia bark, has no diazepam-like side-effects in mice. Journal of Pharmacy and Pharmacology. DOI
  4. (). Honokiol promotes non-rapid eye movement sleep via the benzodiazepine site of the GABA(A) receptor in mice. British Journal of Pharmacology. DOI