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Magnolia Bark Dosage Guide

Evidence:Emerging
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This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

200-500mg standardized magnolia bark extract daily, or 250mg Relora 2-3 times daily

Maximum dose: 750mg/day Relora or 500mg/day concentrated magnolia extract (limited data above these levels)

Dosage Recommendations

General recommendation: 200-500mg standardized magnolia bark extract daily, or 250mg Relora 2-3 times daily

Timing: For stress: divided doses throughout the day. For sleep: single dose 30-60 minutes before bed.

Dosage by Condition

Stress and cortisol management
250mg Relora, 3 times daily (750mg total)Emerging
Sleep support
200-400mg magnolia bark extract before bedEmerging
Anxiety
200-500mg standardized extract dailyEmerging

Upper limit: 750mg/day Relora or 500mg/day concentrated magnolia extract (limited data above these levels)

Timing & Absorption

For stress: divided doses throughout the day. For sleep: single dose 30-60 minutes before bed.

Can be taken with or without food.

Full Magnolia Bark Guide

References

  1. RCTTalbott SM, Talbott JA, Pugh M (2013). Effect of Magnolia officinalis and Phellodendron amurense (Relora) on cortisol and psychological mood state in moderately stressed subjects. Journal of the International Society of Sports Nutrition. DOI PubMed
  2. In-vitroAlexeev M, Grosenbaugh DK, Bhatt MH, et al. (2012). The natural products magnolol and honokiol are positive allosteric modulators of both synaptic and extra-synaptic GABA(A) receptors. Neuropharmacology. DOI PubMed
  3. ReviewThomas AJ, Ismail R, Taylor-Swanson L, Cray L, et al. (2014). Effects of isoflavones and amino acid therapies for hot flashes and co-occurring symptoms during the menopausal transition and early postmenopause: a systematic review.. Maturitas. DOI PubMed
  4. RCTAgosta C, Atlante M, Benvenuti C (2011). Randomized controlled study on clinical efficacy of isoflavones plus Lactobacillus sporogenes, associated or not with a natural anxiolytic agent in menopause.. Minerva ginecologica. PubMed