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Types of Magnolia Bark: Forms & Bioavailability

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Forms Comparison

FormBioavailabilityBest For
Relora (Magnolia + Phellodendron Extract)ModerateStress and cortisol — the most clinically studied standardized preparation
Standardized Magnolia Bark Extract (2% honokiol)ModerateSleep and anxiety — focused on the primary anxiolytic compound honokiol
High-Honokiol Extract (90%+ honokiol)HighTargeted GABA modulation — concentrated honokiol for potent anxiolytic and sleep effects

Relora (Magnolia + Phellodendron Extract)

Bioavailability: Moderate. Best for: Stress and cortisol — the most clinically studied standardized preparation.

Standardized Magnolia Bark Extract (2% honokiol)

Bioavailability: Moderate. Best for: Sleep and anxiety — focused on the primary anxiolytic compound honokiol.

High-Honokiol Extract (90%+ honokiol)

Bioavailability: High. Best for: Targeted GABA modulation — concentrated honokiol for potent anxiolytic and sleep effects.

Full Magnolia Bark Guide

References

  1. (). Effect of Magnolia officinalis and Phellodendron amurense (Relora) on cortisol and psychological mood state in moderately stressed subjects. Journal of the International Society of Sports Nutrition. DOI
  2. (). The natural products magnolol and honokiol are positive allosteric modulators of both synaptic and extra-synaptic GABA(A) receptors. Neuropharmacology. DOI
  3. (). Honokiol, a putative anxiolytic agent extracted from magnolia bark, has no diazepam-like side-effects in mice. Journal of Pharmacy and Pharmacology. DOI
  4. (). Honokiol promotes non-rapid eye movement sleep via the benzodiazepine site of the GABA(A) receptor in mice. British Journal of Pharmacology. DOI