Manganese — Frequently Asked Questions
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Frequently Asked Questions
Is manganese the same as magnesium?
Is manganese the same as magnesium?
No. Despite similar names, manganese (Mn) and magnesium (Mg) are different minerals with distinct functions. Magnesium is needed in much larger amounts (300-400mg/day) and is involved in 300+ enzymatic reactions. Manganese is a trace mineral needed in tiny amounts (2-5mg/day) and is most important for mitochondrial antioxidant defense and bone formation.
Can manganese supplements be dangerous?
Can manganese supplements be dangerous?
At recommended doses (2-5mg/day), manganese supplements are safe for healthy individuals. The upper limit is 11mg/day. Chronic excessive intake can cause manganism, a neurological condition with symptoms similar to Parkinson's disease. People with liver disease should be especially cautious, as the liver is responsible for excreting excess manganese via bile.
Do I need a manganese supplement?
Do I need a manganese supplement?
Most people do not. Manganese is found in whole grains, nuts, leafy vegetables, and tea. Deficiency is extremely rare. Supplementation is mainly used in bone-support formulas and multivitamins at low doses (2-5mg). If your diet includes whole grains and nuts, you likely get adequate manganese.
References
- Strause L, Saltman P, Smith KT, Bracker M, Andon MB (1994). Spinal bone loss in postmenopausal women supplemented with calcium and trace minerals. Journal of Nutrition. DOI PubMed
- Aschner JL, Aschner M (2005). Nutritional aspects of manganese homeostasis. Molecular Aspects of Medicine. DOI PubMed
- O'Neal SL, Zheng W (2015). Manganese toxicity upon overexposure: a decade in review. Current Environmental Health Reports. DOI PubMed