General Dosage
500mg standardized extract daily or 45 drops tincture daily, divided into 2-3 doses
Maximum dose: 1,000mg extract/day (limited data above this level)
Passionflower Dosage Guide
Evidence:Moderate
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Dosage Recommendations
General recommendation: 500mg standardized extract daily or 45 drops tincture daily, divided into 2-3 doses
Timing: For anxiety: divided doses throughout the day. For sleep: single dose 30-60 minutes before bed.
Dosage by Condition
Generalized anxiety
500mg extract or 45 drops tincture daily, dividedModerate
Pre-surgical / acute anxiety
500mg extract, 60-90 minutes before eventModerate
Sleep quality
500mg extract or 1 cup tea, 30-60 min before bedModerate
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Generalized anxiety | 500mg extract or 45 drops tincture daily, divided | Moderate |
| Pre-surgical / acute anxiety | 500mg extract, 60-90 minutes before event | Moderate |
| Sleep quality | 500mg extract or 1 cup tea, 30-60 min before bed | Moderate |
Upper limit: 1,000mg extract/day (limited data above this level)
Timing & Absorption
For anxiety: divided doses throughout the day. For sleep: single dose 30-60 minutes before bed.
Can be taken with or without food.
References
- RCTAkhondzadeh S, Naghavi HR, Vazirian M, Shayeganpour A, Rashidi H, Khani M (2001). Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam. Journal of Clinical Pharmacy and Therapeutics. DOI PubMed
- RCTNgan A, Conduit R (2011). A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality. Phytotherapy Research. DOI PubMed
- RCTDodd F, Kennedy D, Wightman E, Khan J, et al. (2022). The chronic effects of a combination of herbal extracts (Euphytose®) on psychological mood state and response to a laboratory stressor: A randomised, placebo-controlled, double blind study in healthy humans.. Journal of psychopharmacology (Oxford, England). DOI PubMed
- ReviewLakhan SE, Vieira KF (2010). Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review.. Nutrition journal. DOI PubMed
- ReviewMeolie AL, Rosen C, Kristo D, Kohrman M, et al. (2005). Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence.. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. PubMed