General Dosage
100-200mg daily, taken as needed (not daily due to rapid tolerance)
Maximum dose: 300mg/day (tolerance develops rapidly with daily use)
Phenylpiracetam Dosage Guide
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Dosage Recommendations
General recommendation: 100-200mg daily, taken as needed (not daily due to rapid tolerance)
Timing: Morning or early afternoon; as-needed use preferred to prevent tolerance; avoid daily long-term use
Dosage by Condition
Cognitive enhancement
100-200mg as neededEmerging
Physical performance
100-200mg 1-2 hours before activityEmerging
Fatigue and cognitive recovery
200mg daily for limited periodsEmerging
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Cognitive enhancement | 100-200mg as needed | Emerging |
| Physical performance | 100-200mg 1-2 hours before activity | Emerging |
| Fatigue and cognitive recovery | 200mg daily for limited periods | Emerging |
Upper limit: 300mg/day (tolerance develops rapidly with daily use)
Timing & Absorption
Morning or early afternoon; as-needed use preferred to prevent tolerance; avoid daily long-term use
Can be taken with or without food.
References
- Savchenko AY, Zakharova NS, Stepanov IN (2005). The phenotropil treatment of the consequences of brain organic lesions. Zhurnal Nevrologii i Psikhiatrii imeni SS Korsakova. PubMed
- Malykh AG, Sadaie MR (2010). Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders. Drugs. DOI PubMed
- Firstova YY, Abaimov DA, Kapitsa IG, et al. (2011). The effects of scopolamine and the nootropic drug phenotropil on rat brain neurotransmitter receptors during testing of the conditioned passive avoidance task. Neurochemical Journal. DOI